A4YJE9 · IF2_BRASO

Function

function

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

Features

Showing features for binding site.

1921100200300400500600700800900
TypeIDPosition(s)Description
Binding site426-433GTP (UniProtKB | ChEBI)
Binding site474-478GTP (UniProtKB | ChEBI)
Binding site528-531GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionguanosine tetraphosphate binding
Molecular Functiontranslation initiation factor activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Translation initiation factor IF-2

Gene names

    • Name
      infB
    • Ordered locus names
      BRADO0053

Organism names

Accessions

  • Primary accession
    A4YJE9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000082071-921Translation initiation factor IF-2

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-296Disordered
Compositional bias22-36Polar residues
Compositional bias40-58Basic and acidic residues
Compositional bias65-83Pro residues
Compositional bias103-182Basic and acidic residues
Domain417-586tr-type G
Region426-433G1
Region451-455G2
Region474-477G3
Region528-531G4
Region564-566G5

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    921
  • Mass (Da)
    98,625
  • Last updated
    2007-05-29 v1
  • Checksum
    F94D6A5835AAC2DA
MADQNTPGDKKLGVPSKTLTLKPRVETGTVRQSFPHGRSKQVVVEKRGTKRRVGDGAPDAPHAPEPTVAKAPPPPPPSNRPSGPRPSGGQQRGGSGVVLRTLTEDERSARASALADARVRDLEERRQAEEEARRRAEREAAERAEREAAEARRKAEEERHRHEEEAKRKAELEAKKRFGEGEAPRPAAAAPQPTVSAPARPAQAPGRPQGAPGSRPQQIGGPSSRPGGSQPGGARPAGPRPAGGGPLGRAPAAVAAGPDEDEGPRQIRRGPGGAARPAPPPKTTHKPGPQKQRGRLTVVTALNADDVRERSIASFRRRTQRLKGHAANEQKEKLVREVTIPEAITIQELANRMSERAVDVIRLLMRQGAMHKITDVIDADTAQLIAEELGHTVKRVAASDVEEGLFDVVDDSTDTEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGEAGGITQHIGAYQVTAPDSGKKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTIEAINHAKAAKVPMIVAINKIDKPDARPERVRTELLQHEVQVESLGGDVVDVEVSAKNKTNLDRLLEMIALQADILDLKTNSDRPAEGTVIEAKLDRGRGPVATVLVQRGTLRVGDIIVAGAEMGRVRALISDQGETLQEAGPSVPVEVLGFNGPPEAGDRLAVVENEARARQVTSYRAHQKRENAAASISGMRGSLEQMMSQLKTAGRKEFPLVIKADVQGSLEAILGSLEKLGTEEVAARILHAGVGGISESDVTLAEGFNAAIIGFSVRANKEAAALAKRNGIEIRYYNIIYDLVDDVKKAMSGLLAPTLRETMLGNAQILEVFNISKVGKVAGCRVTDGTVERGANVRLIRDNVVVHEGKLSTLKRFKDEVKDVQAGQECGMAFENYGDMRVGDVIECYRVETIQRSL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias22-36Polar residues
Compositional bias40-58Basic and acidic residues
Compositional bias65-83Pro residues
Compositional bias103-182Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU234118
EMBL· GenBank· DDBJ
CAL74025.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp