A4WMA6 · TF2B_PYRAR

Function

function

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

Features

Showing features for binding site.

133350100150200250300
TypeIDPosition(s)Description
Binding site37Zn2+ (UniProtKB | ChEBI)
Binding site40Zn2+ (UniProtKB | ChEBI)
Binding site56Zn2+ (UniProtKB | ChEBI)
Binding site59Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenttranscription preinitiation complex
Molecular FunctionDNA-binding transcription factor activity
Molecular FunctionTBP-class protein binding
Molecular Functionzinc ion binding
Biological Processtranscription preinitiation complex assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription initiation factor IIB
  • Short names
    TFIIB

Gene names

    • Name
      tfb
    • Ordered locus names
      Pars_1976

Organism names

Accessions

  • Primary accession
    A4WMA6

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000801151-333Transcription initiation factor IIB

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for zinc finger, repeat.

Type
IDPosition(s)Description
Zinc finger33-64TFIIB-type
Repeat149-2321
Repeat243-3242

Sequence similarities

Belongs to the TFIIB family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    333
  • Mass (Da)
    37,473
  • Last updated
    2007-05-29 v1
  • Checksum
    9D31DB6955D05AE7
MSSTSLPSSGKPLKLRINRDSEGYLSLVTESGEIYRCPICGNDRFVYNYERGEVVCIVCGAVVQEQLLDLGPEWRAFTSEEKGQRARTGAPLTRLISEALTTVIDWRDKDVSGRELDIKRKLEVIRLRKWQTRARVQTSYERNFIQAAQELERLKSSMGVPRPCVEQALEIYRQALEKELVRGRSVEAMAAAALYMACRMMRMPRPLDELVRYTKASRREVARCYRLLLRELNVKVPISDPVLYISRIAEQLKLSGEVVKAAIDILQRAKKAGITAGKDPAGLAAAAVYIASLMHGDNRTQKDFAVAAGVTEVTVRNRYKELAKALNIKVPVK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000660
EMBL· GenBank· DDBJ
ABP51523.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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