A4W7Z1 · MTNA_ENT38
- ProteinMethylthioribose-1-phosphate isomerase
- GenemtnA
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids342 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
Catalytic activity
- S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 49-51 | substrate | ||||
Sequence: RGA | ||||||
Binding site | 86 | substrate | ||||
Sequence: R | ||||||
Site | 148 | Transition state stabilizer | ||||
Sequence: C | ||||||
Binding site | 187 | substrate | ||||
Sequence: Q | ||||||
Active site | 228 | Proton donor | ||||
Sequence: D | ||||||
Binding site | 238-239 | substrate | ||||
Sequence: NK |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | S-methyl-5-thioribose-1-phosphate isomerase activity | |
Biological Process | L-methionine salvage from methylthioadenosine | |
Biological Process | L-methionine salvage from S-adenosylmethionine |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethylthioribose-1-phosphate isomerase
- EC number
- Short namesM1Pi ; MTR-1-P isomerase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Enterobacter
Accessions
- Primary accessionA4W7Z1
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000357182 | 1-342 | Methylthioribose-1-phosphate isomerase | |||
Sequence: MQTLQTTSLRVADNQLFILDQQALPQEKRWLDASTVEALVGHIHALRVRGAPLIGLSASLLLALLAENGHSRDQLAVALDTLRASRPTAVNLMNNLDRMKQALWQEDFVPALVTEALRLIEEDKQLCDAIARAGSQLVKPGSRLLTHCNTGGLATAGVGTALGVIAHAFAAGNVNNVWVDETRPLLQGGRLTAWELGELGVPYQLITDSMAASLMAKGQVDAVWVGADRIAANGDVANKIGTYSLAVLAKFHGIPFYVAAPQTTLDPHCPNGEAIPIEQRDAREVTGVAGSFGAVQWAPENAQVYNPAFDVTPAALISGWVLDTGVVLPEAVEQGVFKSSAV |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length342
- Mass (Da)36,313
- Last updated2007-05-29 v1
- Checksum91BBDCFA414CBDF3
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000653 EMBL· GenBank· DDBJ | ABP59821.1 EMBL· GenBank· DDBJ | Genomic DNA |