A4T0J1 · KATG_POLAQ

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site90Transition state stabilizer
Active site94Proton acceptor
Binding site262Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • Ordered locus names
      Pnuc_2044

Organism names

Accessions

  • Primary accession
    A4T0J1

Proteomes

PTM/Processing

Features

Showing features for signal, chain, cross-link.

TypeIDPosition(s)Description
Signal1-12
ChainPRO_000035486013-717Catalase-peroxidase
Cross-link93↔221Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-247)
Cross-link221↔247Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-93)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Structure

Family & Domains

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    717
  • Mass (Da)
    79,677
  • Last updated
    2007-05-15 v1
  • Checksum
    123162FCD1A2A41B
MTSKGMCPVAHGANTEASETPMAWWPKALNLDILHQQDTKTNPMGSSFSYRDELKKLDVGALKKDMKDLLTNSQDWWPADWGHYGGLMIRMAWHSAGSYRIADGRGGAGTGNQRFAPINSWPDNANLDKARRLLWPIKKKYGNKISWADLMILAGTIAYESMGLKTFGFSFGREDIWHPEKDIYWGSEKEWLQKSGGKGSRYSGERELSNPLAAVMMGLIYVNPEGVDGKPDPLKTAQDMRVTFARMAMNDEETVALTAGGHTVGKAHGNGNAANLGPAPEAAPIDEQGLGWMNHKTRGIGRDAVTSGLEGAWTTHPTQWDNGYFNLLLNYDWKLTESPAGAHQYEPINIKEEDKPVDVEDASIRCMPMMTDADIALKMDPEYRKISERFSKDQAYFSETFAKAWFKLTHRDMGPKARYFGPDVPKEELIWQDPIPSGPKSYDIDAVKAKIKASGLSMSDMVTTAWDSARTFRGSDKRGGANGARIRLAPQKDWMGNEPERLARVLAVYEKIGKECGISIADTIILGGNIGIEQAAKAGGFDVKVPFTSGRGDAIQAMTDVESFEVLEPLADGFRNWLKESYVVTPEELLLDRTQLMGLTAQEMTVLIGGMRVLGTNYGGSKQGVFTEKEGVLSNDFFVNLTDMNYLWKPTGQNSYDIVERNTEKTKWTATRADLVFGSNSILRAYAEVYAQDDNKEKFVNDFIAAWTKVMNADLFN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000655
EMBL· GenBank· DDBJ
ABP35255.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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