A4QQE0 · CLP1_PYRO7

Function

function

Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

Caution

May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.

Features

Showing features for binding site.

145550100150200250300350400450
TypeIDPosition(s)Description
Binding site28ATP (UniProtKB | ChEBI)
Binding site67ATP (UniProtKB | ChEBI)
Binding site137-142ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentmRNA cleavage factor complex
Molecular FunctionATP binding
Molecular Functionpolynucleotide 5'-hydroxyl-kinase activity
Biological ProcessmRNA 3'-end processing
Biological ProcesstRNA splicing, via endonucleolytic cleavage and ligation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    mRNA cleavage and polyadenylation factor CLP1

Gene names

    • Name
      CLP1
    • ORF names
      MGG_08804

Organism names

Accessions

  • Primary accession
    A4QQE0
  • Secondary accessions
    • G4NFJ3

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003752091-455mRNA cleavage and polyadenylation factor CLP1

Interaction

Subunit

Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region112-131Disordered

Sequence similarities

Belongs to the Clp1 family. Clp1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    455
  • Mass (Da)
    48,583
  • Last updated
    2012-01-25 v2
  • Checksum
    934321CF66D799AE
MSIPGLGLIPEKPATSASRTYTLEPRQEYRFSVSHGASITITLTRGTAERDGTELALNVAYTLSGVKSKILSWHGANLSIEGITDHESVAGPDDAANTAHLNLHAFLQRSREAAARNNGGGRSAPHGPRVLVAGKTGCGRTSLVRTLAAWATRTGAQPMVVDADPGEGLLTLPGTLSAAVFGTVMDVASEGGWGAAPSSGPSAVPVKLPLVFYYGRRRVEEDRDLYKGVVNSISSAISARAADDPAVRSAGMLIDTPPYVEGKGADVLIHIAEELNVNIIVTIDTPSLHTELTQRFSGVKNVLGEHVSVVALDKSSGVMERDEGFLQHMGEASIKEYFFGDAKITLSPFTQQVAFDELAIYTSPEASDYSAEPGALERIPQPLPEMAHWVLAMMDAAPNDPPHKIRYAPVSGFVYVAAVDKERRRMKILAPVSGRLGDKPLVWGKWPEPHINLLG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM001236
EMBL· GenBank· DDBJ
EHA46800.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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