A4L2T8 · A4L2T8_LIMRT
- Protein3-oxoacyl-[acyl-carrier-protein] reductase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids244 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
Catalytic activity
- a (3R)-hydroxyacyl-[ACP] + NADP+ = a 3-oxoacyl-[ACP] + NADPH + H+
Pathway
Lipid metabolism; fatty acid biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 12-15 | NADP+ (UniProtKB | ChEBI) | |||
Binding site | 89 | NADP+ (UniProtKB | ChEBI) | |||
Active site | 154 | Proton acceptor | |||
Binding site | 154-158 | NADP+ (UniProtKB | ChEBI) | |||
Binding site | 187 | NADP+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity | |
Molecular Function | NAD binding | |
Biological Process | fatty acid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-oxoacyl-[acyl-carrier-protein] reductase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Limosilactobacillus
Accessions
- Primary accessionA4L2T8
Interaction
Subunit
Homotetramer.
Structure
Sequence
- Sequence statusComplete
- Length244
- Mass (Da)26,377
- Last updated2007-05-01 v1
- MD5 ChecksumCF640FDC182FA244575EC6C13DBBEE3C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
EF421909 EMBL· GenBank· DDBJ | ABO43827.1 EMBL· GenBank· DDBJ | Genomic DNA |