A4GKN6 · A4GKN6_9POAL
- ProteinNAD(P)H-quinone oxidoreductase subunit 5, chloroplastic
- GenendhF
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids641 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Catalytic activity
- a plastoquinone + (n+1) H+(in) + NADH = a plastoquinol + n H+(out) + NAD+
a plastoquinone RHEA-COMP:9562 + (n+1) H+ (in)CHEBI:15378+ CHEBI:57945 = a plastoquinol RHEA-COMP:9561 + n H+ (out)CHEBI:15378+ CHEBI:57540 - a plastoquinone + (n+1) H+(in) + NADPH = a plastoquinol + n H+(out) + NADP+
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chloroplast thylakoid membrane | |
Cellular Component | mitochondrial respiratory chain complex I | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Molecular Function | NADH dehydrogenase activity | |
Molecular Function | quinone binding | |
Biological Process | ATP synthesis coupled electron transport | |
Biological Process | electron transport coupled proton transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD(P)H-quinone oxidoreductase subunit 5, chloroplastic
- EC number
- Alternative names
Gene names
Encoded on
- Chloroplast
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Restionaceae > Aphelia
Accessions
- Primary accessionA4GKN6
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Plastid, chloroplast thylakoid membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-24 | Helical | ||||
Sequence: PFSISILIGFGLIFIPTVI | ||||||
Transmembrane | 36-56 | Helical | ||||
Sequence: ILLLNITIIFASNLSIQQIKG | ||||||
Transmembrane | 76-100 | Helical | ||||
Sequence: FGYIIDPLTSIMPILISTVGIMVFI | ||||||
Transmembrane | 112-130 | Helical | ||||
Sequence: YVRFFVYISLFNASMLGLV | ||||||
Transmembrane | 136-158 | Helical | ||||
Sequence: IQIYFFWELVGICSYLLIGFWFT | ||||||
Transmembrane | 170-191 | Helical | ||||
Sequence: FVTNRVGDFGLLLGILGFYWIT | ||||||
Transmembrane | 211-230 | Helical | ||||
Sequence: GFYSLFTILCAFLLFMGAFA | ||||||
Transmembrane | 251-272 | Helical | ||||
Sequence: ISALIHAATMVAAGIFLIARLF | ||||||
Transmembrane | 284-302 | Helical | ||||
Sequence: FISLIGVITLLLGGTLALA | ||||||
Transmembrane | 318-339 | Helical | ||||
Sequence: LGYMMLALGIGSYQAALFHLIT | ||||||
Transmembrane | 345-366 | Helical | ||||
Sequence: ALLFLGSGSIIHSMEPIVGYST | ||||||
Transmembrane | 387-408 | Helical | ||||
Sequence: ISFLLGTLSLCGIPPLACFWSK | ||||||
Transmembrane | 420-438 | Helical | ||||
Sequence: PVLAIIAFSTAGLTAFYMF | ||||||
Transmembrane | 544-563 | Helical | ||||
Sequence: MLFPLILLVLFTSFVGFIGI | ||||||
Transmembrane | 596-621 | Helical | ||||
Sequence: FSYFFANAIFSISIAILGLFIAQILY |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 66-116 | NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal | ||||
Sequence: WIINNDFCFEFGYIIDPLTSIMPILISTVGIMVFIYSDNYMFYDQGYVRFF | ||||||
Domain | 132-432 | NADH:quinone oxidoreductase/Mrp antiporter membrane subunit | ||||
Sequence: SSNLIQIYFFWELVGICSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFQISNNPIDNNGFYSLFTILCAFLLFMGAFAKSAQFPLHIWLPDAMEGPTPISALIHAATMVAAGIFLIARLFPILITIPHISNFISLIGVITLLLGGTLALAQRDIKKSLAYSTMSQLGYMMLALGIGSYQAALFHLITHAYSKALLFLGSGSIIHSMEPIVGYSTKKNQNMILMGGLKKYIPITKISFLLGTLSLCGIPPLACFWSKDEILSDSWLHSPVLAIIAFSTAGL | ||||||
Domain | 439-640 | NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal | ||||
Sequence: RIYLLTFDGYLHVHFQDYSNTKNNLIYSISLWGKTKFKRLKKDAPLLRVNKEVYFFTKKSFNIFKNIKNKNNVINTVDKIQQYNNTSFANENQYTSVYPQESDNTMLFPLILLVLFTSFVGFIGIDFFQGSVNFNILEKWLTSSINLYHESANFSNKFSYFFANAIFSISIAILGLFIAQILYGSTYSFFKNLDLMNSLEKI |
Sequence similarities
Belongs to the complex I subunit 5 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length641
- Mass (Da)72,622
- Last updated2007-04-17 v1
- ChecksumB8BC1886435583E0
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: I | ||||||
Non-terminal residue | 641 | |||||
Sequence: N |