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A4D9E7 · A4D9E7_ASPFU

Function

function

Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcyclin/CDK positive transcription elongation factor complex
Cellular Componentnucleus
Molecular Functioncyclin-dependent protein serine/threonine kinase activator activity
Biological Processpositive regulation of DNA-templated transcription, elongation
Biological Processregulation of transcription by RNA polymerase II

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Cyclin, putative

Gene names

    • ORF names
      AFUA_3G10070

Organism names

Accessions

  • Primary accession
    A4D9E7

Proteomes

Interaction

Subunit

Component of the SRB8-11 complex, a regulatory module of the Mediator complex.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain60-166Cyclin-like
Domain183-266Cyclin-like
Region279-559Disordered
Compositional bias311-328Basic and acidic residues
Compositional bias355-388Polar residues
Compositional bias472-501Basic and acidic residues
Compositional bias509-542Pro residues

Sequence similarities

Belongs to the cyclin family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    559
  • Mass (Da)
    62,200
  • Last updated
    2007-04-17 v1
  • MD5 Checksum
    0F45BFE0ADF62ED5852001E44958D0D4
MASAPSHSSQKRPLPAEPNPVLHASQTQWLFTDEELTRTPSQLDGMKMEAEHTSRSKGVNFITQVGIMLKLPQLTLATAAVYLHRFFMRYSMVDIPQRPGMHPYPIAATALFLATKVEENVRRMRELVVACCRVAQKQPNLVVDEQSKEFWKWRDTILHHEDLLLEALCFDLQLEQPYRILYDFICFFGVNDNKPLRNAAWAFVNDSMFTVLCLQFTARTIAAAALYAAARHCDVGFPDDDRGRAWWEQIDVDLTQVRRACMRMAQLYENNAMQKHSQYYPTTPILSDEGTEKTRIPHAGSPANLPPAESDVTHGRKRSKEPEDSGEPRGDGSAPSNGERSPKRPRRDADAAPRGSWQDQQSPSAPSSQSLPNAGSPSSSSQGRPHLNGQAPPSLPHPPVHHRHPHPLPPAPRPFPRRDSDHHPPGGGKVAGPREADPIQQRIDEIVSQNMPSHGAPPVPPPSGAGARIPNRRNSVDRRGPDRYRGYEDPARRRRSSFGRRSQSFEEQPPPLPGHPHHQPLPPPPPPPDIPQPPPPPPPSQTQQAAQEDEGGGSEEGEL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias311-328Basic and acidic residues
Compositional bias355-388Polar residues
Compositional bias472-501Basic and acidic residues
Compositional bias509-542Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAHF01000002
EMBL· GenBank· DDBJ
EBA27465.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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