A4D0R5 · A4D0R5_HUMAN
- ProteintRNA-dihydrouridine synthase
- GenePP35
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids317 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 33-35 | FMN (UniProtKB | ChEBI) | |||
Binding site | 87 | FMN (UniProtKB | ChEBI) | |||
Active site | 116 | Proton donor | |||
Binding site | 186 | FMN (UniProtKB | ChEBI) | |||
Binding site | 240-241 | FMN (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | tRNA dihydrouridine synthase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-dihydrouridine synthase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA4D0R5
Organism-specific databases
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length317
- Mass (Da)35,816
- Last updated2007-04-03 v1
- MD5 Checksum9357CC6DBDCCC0389FF5DF5F7B3BF3F2
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH236947 EMBL· GenBank· DDBJ | EAL24391.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH471070 EMBL· GenBank· DDBJ | EAW83401.1 EMBL· GenBank· DDBJ | Genomic DNA |