A3YTN4 · A3YTN4_9SYNE
- ProteinNAD(P)H-quinone oxidoreductase subunit K
- GenendhK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids253 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
Catalytic activity
- a plastoquinone + (n+1) H+(in) + NADH = a plastoquinol + n H+(out) + NAD+
a plastoquinone RHEA-COMP:9562 + (n+1) H+ (in)CHEBI:15378+ CHEBI:57945 = a plastoquinol RHEA-COMP:9561 + n H+ (out)CHEBI:15378+ CHEBI:57540 - a plastoquinone + (n+1) H+(in) + NADPH = a plastoquinol + n H+(out) + NADP+
Cofactor
Note: Binds 1 [4Fe-4S] cluster.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane respiratory chain complex I | |
Cellular Component | plasma membrane-derived thylakoid membrane | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | iron ion binding | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Molecular Function | quinone binding | |
Biological Process | aerobic respiration | |
Biological Process | electron transport coupled proton transport | |
Biological Process | photosynthesis, light reaction |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD(P)H-quinone oxidoreductase subunit K
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Synechococcaceae > Synechococcus
Accessions
- Primary accessionA3YTN4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cellular thylakoid membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 69-179 | NADH:ubiquinone oxidoreductase-like 20kDa subunit | ||||
Sequence: CCFIEFAALIGSRFDFDRFGLVPRSSPRQADLLITAGTVTMKMAPALVRLYEQMPEPKYVIAMGACTITGGMFSADSTTAVRGVDKLIPVDLYIPGCPPRPEAIFDAVIKL |
Sequence similarities
Belongs to the complex I 20 kDa subunit family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length253
- Mass (Da)27,064
- Last updated2007-04-03 v1
- Checksum45DF87050ADD3C57
Keywords
- Technical term