Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases.Leeuw T., Wu C., Schrag J.D., Whiteway M., Thomas D.Y., Leberer E.View abstractCategoriesInteractionSourceMGI: 1339656PubMedEurope PMCNature 391:191-195 (1998)Cited in1Mapped to10
Identification of a mouse p21Cdc42/Rac activated kinase.Bagrodia S., Taylor S.J., Creasy C.L., Chernoff J., Cerione R.A.View abstractCategoriesInteractionSourceMGI: 1339656PubMedEurope PMCJ. Biol. Chem. 270:22731-22737 (1995)Cited in1Mapped to13
A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases.Burbelo P.D., Drechsel D., Hall A.View abstractCategoriesInteractionSourceMGI: 1339656PubMedEurope PMCJ Biol Chem 270:29071-29074 (1995)Mapped to16
SIRT1 regulates cardiomyocyte alignment during maturation.Fang Y., Fan W., Xu X., Janoshazi A.K., Fargo D.C., Li X.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCJ Cell Sci 135:jcs259076-jcs259076 (2022)Mapped to58
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation.Tan X., Tong L., Li L., Xu J., Xie S., Ji L., Fu J., Liu Q., Shen S.[...], Li X.View abstractCategoriesFunction, ExpressionSourceMGI: 1339656PubMedEurope PMCNat Commun 12:4853-4853 (2021)Mapped to40
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.Bedogni F., Hevner R.F.View abstractCategoriesSequencesSourceMGI: 1339656PubMedEurope PMCFront Mol Neurosci 14:686034-686034 (2021)Mapped to99+
Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons.Hada K., Wulaer B., Nagai T., Itoh N., Sawahata M., Sobue A., Mizoguchi H., Mori D., Kushima I.[...], Yamada K.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCMol Brain 14:21-21 (2021)Mapped to26
The intellectual disability PAK3 R67C mutation impacts cognitive functions and adult hippocampal neurogenesis.Castillon C., Gonzalez L., Domenichini F., Guyon S., Da Silva K., Durand C., Lestaevel P., Vaillend C., Laroche S.[...], Poirier R.View abstractCategoriesNames, Function, Phenotypes & VariantsSourceMGI: 1339656PubMedEurope PMCHum Mol Genet 29:1950-1968 (2020)Mapped to9
Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation.Yang C.Y., Yu T.H., Wen W.L., Ling P., Hsu K.S.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCJ Neurosci 39:4959-4975 (2019)Mapped to99+
Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex.Liu J., Liu Y., Shao J., Li Y., Qin L., Shen H., Xie Y., Xia W., Gao W.Q.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCCell Death Differ 26:2479-2492 (2019)Mapped to59
Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice.Zhu C., Cheng C., Wang Y., Muhammad W., Liu S., Zhu W., Shao B., Zhang Z., Yan X.[...], Chai R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1339656PubMedEurope PMCFront Mol Neurosci 11:362-362 (2018)Mapped to75
The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.Jaudon F., Raynaud F., Wehrle R., Bellanger J.M., Doulazmi M., Vodjdani G., Gasman S., Fagni L., Dusart I.[...], Schmidt S.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCMol. Biol. Cell 26:2112-2127 (2015)Cited in6Mapped to41
Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.Osipovich A.B., Long Q., Manduchi E., Gangula R., Hipkens S.B., Schneider J., Okubo T., Stoeckert C.J. Jr., Takada S., Magnuson M.A.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCDevelopment 141:2939-2949 (2014)Mapped to99+
Pak3 promotes cell cycle exit and differentiation of beta-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice.Piccand J., Meunier A., Merle C., Jia Z., Barnier J.V., Gradwohl G.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCDiabetes 63:203-215 (2014)Mapped to99+
Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.Sipe C.W., Liu L., Lee J., Grimsley-Myers C., Lu X.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCDevelopment 140:1785-1795 (2013)Mapped to99+
Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small- molecule PAK inhibitor FRAX486.Dolan B.M., Duron S.G., Campbell D.A., Vollrath B., Shankaranarayana Rao B.S., Ko H.Y., Lin G.G., Govindarajan A., Choi S.Y., Tonegawa S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1339656PubMedEurope PMCProc Natl Acad Sci U S A 110:5671-5676 (2013)Mapped to31
The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.Dorrance A.M., De Vita S., Radu M., Reddy P.N., McGuinness M.K., Harris C.E., Mathieu R., Lane S.W., Kosoff R.[...], Williams D.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1339656PubMedEurope PMCBlood 121:2474-2482 (2013)Mapped to19
Histaminylation of glutamine residues is a novel posttranslational modification implicated in G-protein signaling.Vowinckel J., Stahlberg S., Paulmann N., Bluemlein K., Grohmann M., Ralser M., Walther D.J.View abstractCategoriesPTM / ProcessingSourceMGI: 1339656PubMedEurope PMCFEBS Lett. 586:3819-3824 (2012)Cited in3Mapped to14
The p21-activated kinase PAK3 forms heterodimers with PAK1 in brain implementing trans-regulation of PAK3 activity.Combeau G., Kreis P., Domenichini F., Amar M., Fossier P., Rousseau V., Barnier J.V.View abstractCategoriesInteractionSourceMGI: 1339656PubMedEurope PMCJ Biol Chem 287:30084-30096 (2012)Mapped to13
Alteration of synaptic network dynamics by the intellectual disability protein PAK3.Dubos A., Combeau G., Bernardinelli Y., Barnier J.V., Hartley O., Gaertner H., Boda B., Muller D.View abstractCategoriesFunctionSourceMGI: 1339656PubMedEurope PMCJ Neurosci 32:519-527 (2012)Mapped to10
A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets.Castro D.S., Martynoga B., Parras C., Ramesh V., Pacary E., Johnston C., Drechsel D., Lebel-Potter M., Garcia L.G.[...], Guillemot F.View abstractCategoriesExpressionSourceMGI: 1339656PubMedEurope PMCGenes Dev 25:930-945 (2011)Mapped to99+