A3DC28 · SIGI2_ACET2

Function

function

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity).
This sigma factor is involved in regulation of cellulosomal genes via an external polysaccharide-sensing mechanism (Probable)

Activity regulation

Negatively regulated by the anti-sigma-I factor RsgI2 (By similarity).
Binding of the polysaccharide substrate to RsgI2 may lead to the release and activation of SigI2 (By similarity).

Features

Showing features for dna binding.

126520406080100120140160180200220240260
TypeIDPosition(s)Description
DNA binding211-230H-T-H motif

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionDNA binding
Molecular Functionsigma factor activity
Biological ProcessDNA-templated transcription initiation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    RNA polymerase sigma factor SigI2

Gene names

    • Name
      sigI2
    • Ordered locus names
      Cthe_0268

Organism names

Accessions

  • Primary accession
    A3DC28

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004365161-265RNA polymerase sigma factor SigI2

Expression

Induction

Up-regulated in the presence of cellulose.

Interaction

Subunit

Interacts with RsgI2.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif71-84Polymerase core binding

Sequence similarities

Belongs to the sigma-70 factor family. SigI subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    265
  • Mass (Da)
    30,744
  • Last updated
    2007-03-20 v1
  • Checksum
    2E5C873D33395AC9
MIDLFSPKGKKDTVSTTNKDKSFEDGIVNIINKIKAGDKLLREEFINSYTPYIIRTVSNLTGKYVDVENSDEFSVGLAAFNEAIDSFDEGKNMFFFKFSTLVIKRRLTDYARHNKKHCHVYPFTYFEDKNNSYFEQIHLKSEIDLQNTYEISREIELYEQKLRDFGISLEHLAKCAPKHKDSKSLCIKIAKVIADNKELFSKLERTRNIPKTELLKLLKINKKTIERNRTFIIAAALIFGNDFNLLKDFLDISEPGGDNIERSTK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000568
EMBL· GenBank· DDBJ
ABN51507.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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