A3DC27 · RSGI2_ACET2
- ProteinAnti-sigma-I factor RsgI2
- GenersgI2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids671 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Anti-sigma factor for SigI2. Negatively regulates SigI2 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI2 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI2.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | cellulose binding | |
Molecular Function | metal ion binding | |
Biological Process | carbohydrate metabolic process |
Keywords
- Ligand
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameAnti-sigma-I factor RsgI2
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Oscillospiraceae > Acetivibrio
Accessions
- Primary accessionA3DC27
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-57 | Cytoplasmic | ||||
Sequence: MSHYTGIILKLESDRAIVLTDGLDFMELKLKPGMQRGQHVIFDESDLYSAGLITRYK | ||||||
Transmembrane | 58-78 | Helical | ||||
Sequence: SIIMPFSAFAAAAAVFLVILF | ||||||
Topological domain | 79-671 | Extracellular | ||||
Sequence: SLRFVSISQEYAYIDVDINPSIGLVIDKKEKVIDAKPLNNDAKPILDEAAPKDMPLYDALSKILDISKKNGYINSADNIVLFSASINSGRNNVSESDKGIQEIISTLKDVAKDAGVKFEIIPSTEEDRQKALDQNLSMGRYAIYVKAVEEGVNLNLEDARNLSVSEILGKVNIGKFAISDTPEDSGIMPAISVPAEPVPSVTPAYTAVPEKTEAQPVDIPKSSPTPASFTAHVPTPPKTPSIPHTSGPAIVHTPAADKTTPTFTGSSTPVPTNVVAIASTPVPVSTPKPVSTPAYSSTPTPESTPVPVSTPKPASTPTPASTPKPVSTPTHVSTPKPISTPTSTPRPASTPKPTSTPTPESTPKPTSTPAPVSTPTSTPIPTYTSTPASTPIPAYTSTPTSIPTLTPATSPAPTSSPTPIPSPAPTETDLLTKIELQAYNHIRTSETKELQPRIKLINTGNTPITLSEVKIRYYYTKDQVINEIYTCDWSNITSSKITGTVVQMSNPKPNADSYVEIGFTNSAGVLNPGEYVEIISRIGNSYALSLATPPYSEWNYMYDQNSDYSFNNSSSDFVVWDKITVYISGTLYWGIEP |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000436545 | 1-671 | Anti-sigma-I factor RsgI2 | |||
Sequence: MSHYTGIILKLESDRAIVLTDGLDFMELKLKPGMQRGQHVIFDESDLYSAGLITRYKSIIMPFSAFAAAAAVFLVILFSLRFVSISQEYAYIDVDINPSIGLVIDKKEKVIDAKPLNNDAKPILDEAAPKDMPLYDALSKILDISKKNGYINSADNIVLFSASINSGRNNVSESDKGIQEIISTLKDVAKDAGVKFEIIPSTEEDRQKALDQNLSMGRYAIYVKAVEEGVNLNLEDARNLSVSEILGKVNIGKFAISDTPEDSGIMPAISVPAEPVPSVTPAYTAVPEKTEAQPVDIPKSSPTPASFTAHVPTPPKTPSIPHTSGPAIVHTPAADKTTPTFTGSSTPVPTNVVAIASTPVPVSTPKPVSTPAYSSTPTPESTPVPVSTPKPASTPTPASTPKPVSTPTHVSTPKPISTPTSTPRPASTPKPTSTPTPESTPKPTSTPAPVSTPTSTPIPTYTSTPASTPIPAYTSTPTSIPTLTPATSPAPTSSPTPIPSPAPTETDLLTKIELQAYNHIRTSETKELQPRIKLINTGNTPITLSEVKIRYYYTKDQVINEIYTCDWSNITSSKITGTVVQMSNPKPNADSYVEIGFTNSAGVLNPGEYVEIISRIGNSYALSLATPPYSEWNYMYDQNSDYSFNNSSSDFVVWDKITVYISGTLYWGIEP |
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-51 | RsgI N-terminal anti-sigma | ||||
Sequence: YTGIILKLESDRAIVLTDGLDFMELKLKPGMQRGQHVIFDESDLYSAG | ||||||
Region | 290-323 | Disordered | ||||
Sequence: TEAQPVDIPKSSPTPASFTAHVPTPPKTPSIPHT | ||||||
Region | 359-505 | Disordered | ||||
Sequence: PVPVSTPKPVSTPAYSSTPTPESTPVPVSTPKPASTPTPASTPKPVSTPTHVSTPKPISTPTSTPRPASTPKPTSTPTPESTPKPTSTPAPVSTPTSTPIPTYTSTPASTPIPAYTSTPTSIPTLTPATSPAPTSSPTPIPSPAPTE | ||||||
Compositional bias | 367-381 | Polar residues | ||||
Sequence: PVSTPAYSSTPTPES | ||||||
Compositional bias | 382-402 | Pro residues | ||||
Sequence: TPVPVSTPKPASTPTPASTPK | ||||||
Compositional bias | 403-417 | Polar residues | ||||
Sequence: PVSTPTHVSTPKPIS | ||||||
Compositional bias | 418-454 | Pro residues | ||||
Sequence: TPTSTPRPASTPKPTSTPTPESTPKPTSTPAPVSTPT | ||||||
Compositional bias | 455-487 | Polar residues | ||||
Sequence: STPIPTYTSTPASTPIPAYTSTPTSIPTLTPAT | ||||||
Compositional bias | 488-502 | Pro residues | ||||
Sequence: SPAPTSSPTPIPSPA | ||||||
Domain | 508-671 | CBM3 | ||||
Sequence: LLTKIELQAYNHIRTSETKELQPRIKLINTGNTPITLSEVKIRYYYTKDQVINEIYTCDWSNITSSKITGTVVQMSNPKPNADSYVEIGFTNSAGVLNPGEYVEIISRIGNSYALSLATPPYSEWNYMYDQNSDYSFNNSSSDFVVWDKITVYISGTLYWGIEP |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length671
- Mass (Da)71,917
- Last updated2007-03-20 v1
- ChecksumA57F84976CB08FCD
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 367-381 | Polar residues | ||||
Sequence: PVSTPAYSSTPTPES | ||||||
Compositional bias | 382-402 | Pro residues | ||||
Sequence: TPVPVSTPKPASTPTPASTPK | ||||||
Compositional bias | 403-417 | Polar residues | ||||
Sequence: PVSTPTHVSTPKPIS | ||||||
Compositional bias | 418-454 | Pro residues | ||||
Sequence: TPTSTPRPASTPKPTSTPTPESTPKPTSTPAPVSTPT | ||||||
Compositional bias | 455-487 | Polar residues | ||||
Sequence: STPIPTYTSTPASTPIPAYTSTPTSIPTLTPAT | ||||||
Compositional bias | 488-502 | Pro residues | ||||
Sequence: SPAPTSSPTPIPSPA |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000568 EMBL· GenBank· DDBJ | ABN51506.1 EMBL· GenBank· DDBJ | Genomic DNA |