A3DBR2 · A3DBR2_ACET2

Function

function

Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t6A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A) at position 37 in tRNAs that read codons beginning with adenine.

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular FunctionN6-threonylcarbomyladenosine methylthiotransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
  • EC number
  • Alternative names
    • tRNA-t(6)A37 methylthiotransferase

Gene names

    • Ordered locus names
      Cthe_0150

Organism names

Accessions

  • Primary accession
    A3DBR2

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-114MTTase N-terminal
Domain139-368Radical SAM core
Domain371-434TRAM

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    434
  • Mass (Da)
    49,691
  • Last updated
    2007-03-20 v1
  • Checksum
    FB7F868991CD2383
MKRAAFYTLGCKVNQYETEAISEMFEKAGYKIVDFEDEADVYVINTCTVTNLSDRKSRQMIRRAKRNNENSIVIVIGCYAQTAPEEVSKIEGVNLVVGTKDRSRILEYLKELETSGGRRNYVGDIMKTREFEELGVNVYKERTRAFIKIQEGCNQFCTYCIIPYARGPVRSRSEENILKEVSGLAHSGYKEVVLTGIHVASYGKDIKNTSLIDIIRKVHEIEGIERIRLGSIEPTTVTEEFVRAIKGMEKLCPQFHISLQSGCDSTLKRMNRKYTTKEYLRSVELLRENLKDVAVTTDVMVGFPGETDEEFNETCRFVEKVLFARMHVFKYSRRKGTPAASYPDQVAPQKKEERSRILIELASRMTLEYNKSFTGRVLPVLFEQEVKGKEGFMEGLTPNYIRVECKGDKDIEGQILNVLLREAKDDYIVGEIVN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000568
EMBL· GenBank· DDBJ
ABN51391.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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