A3CNV6 · AROC_STRSV

Function

function

Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.

Catalytic activity

Cofactor

FMNH2 (UniProtKB | Rhea| CHEBI:57618 )

Note: Reduced FMN (FMNH2).

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site39NADP+ (UniProtKB | ChEBI)
Binding site45NADP+ (UniProtKB | ChEBI)
Binding site130-132FMN (UniProtKB | ChEBI)
Binding site251-252FMN (UniProtKB | ChEBI)
Binding site296FMN (UniProtKB | ChEBI)
Binding site311-315FMN (UniProtKB | ChEBI)
Binding site337FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionchorismate synthase activity
Molecular FunctionFMN binding
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Chorismate synthase
  • EC number
  • Short names
    CS
  • Alternative names
    • 5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

    • Name
      aroC
    • Ordered locus names
      SSA_1467

Organism names

Accessions

  • Primary accession
    A3CNV6

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003224251-388Chorismate synthase

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the chorismate synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    388
  • Mass (Da)
    42,236
  • Last updated
    2007-03-20 v1
  • Checksum
    6452F6D6D73D070E
MRYLTAGESHGPRLTAIIEGVPAGLPLTADYINAELKRRQGGYGRGARMKIESDQVEITSGVRHGLTMGGPITLNVTNLDHQKWQEIMSAADVDEKKKGLRKITKPRPGHADLVGGMKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLEEIGVEVASHIVTFGGIDINVPNNLTVGEIKERAAQSEVSIVNPDREEEIKAYIDQIKKDGDTIGGVIETVVGGVPVGLGSYVQWDKKLDAKIAQGVVSINAFKGVEFGVGFEAGRLKGSQVMDEILWSEEDGFTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKATVERSDPTALPAAGVVMESVVATVLATEVLEKFSSDNLEELKDAVARHREFVKNF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000387
EMBL· GenBank· DDBJ
ABN44861.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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