A2XN66 · CESA2_ORYSI

  • Protein
    Probable cellulose synthase A catalytic subunit 2 [UDP-forming]
  • Gene
    CESA2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Probable catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Pathway

Glycan metabolism; plant cellulose biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site13Zn2+ 1 (UniProtKB | ChEBI)
Binding site16Zn2+ 1 (UniProtKB | ChEBI)
Binding site32Zn2+ 2 (UniProtKB | ChEBI)
Binding site35Zn2+ 2 (UniProtKB | ChEBI)
Binding site40Zn2+ 1 (UniProtKB | ChEBI)
Binding site43Zn2+ 1 (UniProtKB | ChEBI)
Binding site55Zn2+ 2 (UniProtKB | ChEBI)
Binding site58Zn2+ 2 (UniProtKB | ChEBI)
Binding site353UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site359UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site360UDP-alpha-D-glucose (UniProtKB | ChEBI)
Active site389
Binding site389UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site530UDP-alpha-D-glucose (UniProtKB | ChEBI)
Binding site531Mn2+ (UniProtKB | ChEBI)
Binding site555Mn2+ (UniProtKB | ChEBI)
Active site773

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncellulose synthase (UDP-forming) activity
Molecular Functionmetal ion binding
Biological Processcell wall organization
Biological Processcellulose biosynthetic process
Biological Processplant-type cell wall organization or biogenesis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable cellulose synthase A catalytic subunit 2 [UDP-forming]
  • EC number
  • Alternative names
    • OsCesA2

Gene names

    • Name
      CESA2
    • ORF names
      OsI_013509

Organism names

  • Taxonomic identifier
  • Strain
    • cv. 93-11
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    A2XN66

Proteomes

Genome annotation databases

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-270Cytoplasmic
Transmembrane271-291Helical
Topological domain292-293Extracellular
Transmembrane294-314Helical
Topological domain315-856Cytoplasmic
Transmembrane857-877Helical
Topological domain878-882Extracellular
Transmembrane883-903Helical
Topological domain904-918Cytoplasmic
Transmembrane919-939Helical
Topological domain940-969Extracellular
Transmembrane970-990Helical
Topological domain991-1001Cytoplasmic
Transmembrane1002-1022Helical
Topological domain1023-1031Extracellular
Transmembrane1032-1052Helical
Topological domain1053-1073Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003193591-1073Probable cellulose synthase A catalytic subunit 2 [UDP-forming]

PTM databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for zinc finger, region, coiled coil.

TypeIDPosition(s)Description
Zinc finger13-59RING-type; degenerate
Region66-98Disordered
Coiled coil443-470
Region655-676Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,073
  • Mass (Da)
    120,682
  • Last updated
    2007-03-20 v1
  • Checksum
    55B677033E77A7BE
MDGAKSGKQCHVCQICGDGVGTAADGELFTACDVCGFPVCRPCYEYERKDGSQACPQCKTKYKRHKGSPPILGDESDDVDADDASDVNYPTSGNQDHKHKIAERMLTWRMNSGRNDDIVHSKYDSGEIGHPKYDSGEIPRIYIPSLTHSQISGEIPGASPDHMMSPVGNIGRRGHPFPYVNHSPNPSREFSGSLGNVAWKERVDGWKMKDKGAIPMANGTSIAPSEGRGVGDIDASTDYNMEDALLNDETRQPLSRKVPISSSRINPYRMVIVLRLIVLCIFLHYRITNPVRNAYPLWLLSVICEIWFALSWILDQFPKWSPINRETYLDRLALRYDREGEPSQLAPVDIFVSTVDPMKEPPLVTANTVLSILAVDYPVDKVSCYVSDDGAAMLTFDALAETSEFARKWVPFCKKYSIEPRAPEWYFAQKIDYLKDKVQASFVKDRRAMKREYEEFKVRVNALVAKAQKVPEEGWIMQDGTPWPGNNTRDHPGMIQVFLGHSGGLDTEGNELPRLVYVSREKRPGFQHHKKAGAMNALVRVSAVLTNGQYLLNLDCDHYINNSKALREAMCFLMDPNLGRRVCYVQFPQRFDGIDRNDRYANRNTVFFDINLRGLDGLQGPVYVGTGCVFNRTALYGYEPPIKQKRPGYFSSLCGGRKKTKKSKEKSTEKKKSHKHVDSSVPVFNLEDIEEGIEGSGFDDEKSLLMSQMSLEKRFGQSSVFVASTLMEYGGVPQSATPESLLKEAIHVISCGYEDKSDWGTEIGWIYGSVTEDILTGFKMHARGWRSIYCMPKRPAFKGSAPINLSDRLNQVLRWALGSVEILFSRHCPIWYGYGGRLKFLERFAYINTTIYPLTSIPLLLYCILPAICLLTGKFIIPEISNFASIWFISLFLSIFATGILEMRWSGVGIDEWWRNEQFWVIGGISAHLFAVFQGLLKVLAGIDTSFTVTSKASDEEGDFAELYMFKWTTLLIPPTTILIINLVGVVAGISYAINSGYQSWGPLFGKLFFAFWVIVHLYPFLKGLMGRQNRTPTIVVVWAILLASIFSLLWVRIDPFTTRVTGPDTQKCGINC

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM000128
EMBL· GenBank· DDBJ
EAY92276.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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