A2TLL4 · A2TLL4_ORITS

Function

function

May be an adherent factor for rickettsial adsorption to the host-cell surface and a determinant of virulence of individual rickettsial strain. It is the major outer membrane protein.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    56 kDa type-specific antigen
  • Alternative names
    • 56 kDa scrub typhus antigen
    • STA56

Organism names

Accessions

  • Primary accession
    A2TLL4

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-22
ChainPRO_500264657523-53756 kDa type-specific antigen

Family & Domains

Features

Showing features for region, coiled coil.

TypeIDPosition(s)Description
Region114-145Disordered
Coiled coil302-329
Region405-433Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    537
  • Mass (Da)
    57,001
  • Last updated
    2007-03-06 v1
  • Checksum
    73EE76AA378AB0C5
MKKIMLIASAMSALSLPFSASAIELGDEGGLECGPYAKVGVVGGMITGVESTRLDLADADGKKHLSLTTGIPFGGTLAAGMTIAPGFRAELGVMYLTNITAQVTAQVEEGKGKVDSRGEIKADSGGGTDAPIRKRFKLTPPQPTIMPISIADRDFGIDIPNIPQQQAQAAQPQLNDEQRAAARIAWLKNCAGIDYRVKNPNDPNGPMVINPILLNIPQGNPNPVGNPPQRANPPAGFAIHNHEQWRHLVVGLAALSNANKPSASPVKVLSDKISQIYSDIKPFADIAGIDVPDTGLPNSASVEQIQSKMQELNDVLEELRDSFDGYISNAFVNQIQLNFVMPQQAQQQGQGQQQQAQATLQEAVAAAAVRLLNGNDQIAQLYKDLVKLQRHAGIKKAMEKLAAQQEEDAKNQGEGDCKQQQGASEKSKEGGKGKEAEFDLSMIVGQVKLYADLMTTESFSIYAGVGAGLAYTSGKIDGVDIKANTGMVASGALGVAINAAEGVYVDIEGGYMHSFSKIEEKYSVNALMASAGVRYNF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EF213098
EMBL· GenBank· DDBJ
ABN04072.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp