A2SQW3 · METXA_METLZ

Function

function

Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.

Features

Showing features for active site, binding site.

148750100150200250300350400450
TypeIDPosition(s)Description
Active site150Nucleophile
Binding site219substrate
Active site313
Active site346
Binding site347substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionhomoserine O-acetyltransferase activity
Biological Processmethionine biosynthetic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Homoserine O-acetyltransferase
  • EC number
  • Short names
    HAT
  • Alternative names
    • Homoserine transacetylase
      (HTA
      )

Gene names

    • Name
      metXA
    • Ordered locus names
      Mlab_0545

Organism names

Accessions

  • Primary accession
    A2SQW3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004402891-487Homoserine O-acetyltransferase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain45-352AB hydrolase-1
Domain373-430CBS 1
Domain434-487CBS 2

Sequence similarities

Belongs to the AB hydrolase superfamily. MetX family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    487
  • Mass (Da)
    53,097
  • Last updated
    2007-03-06 v1
  • Checksum
    D9881AEA8117FAE3
MLQDSVGEVTTKYHALSVPLSLECGVSLSGVRIAYERYGRADGKNVILVCHPLTGDAHAAGFHKGDTKPGWWDGIIGPGKALDTNRYCVIAANVLGGCKGSTGPSSEDPATGKPYGTTFPVITIRDMVHAEHQLLEDLGISELYAVIGGSMGGMQAMQWSVEFPSFVRRIICIASAGYTTPMHIAFGAVGRAAIMSDPEWNGGNYPAEKKPNHGLSLARMMAHITYLSDESMRTKFGRRLQKQDAFGYGFDTEFSVESYLQHQGETFVERFDPNSYLYITRAVDYYDLTKNGSLTEGLAATQAKFLIISVSSDWLYPPYLSQEIMLALTTNNREARYAEIVSPHGHDGFLLENAQLNYIVGQFLTPMTVEDLMTNNPPSIQETSSIREAAELMIGHEINHLPVVSGNGTLSGIVTSWDIAKSVAGDFQDLAEIMTKDVITIQRSDSLRLAASLMEKHAISALPVVDDSNHVLGMLTSETLSLSEVLQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000559
EMBL· GenBank· DDBJ
ABN06719.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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