A2SM29 · GLPK_METPP

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

149950100150200250300350400450
TypeIDPosition(s)Description
Binding site11ADP (UniProtKB | ChEBI)
Binding site11ATP (UniProtKB | ChEBI)
Binding site11sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site12ATP (UniProtKB | ChEBI)
Binding site13ATP (UniProtKB | ChEBI)
Binding site15ADP (UniProtKB | ChEBI)
Binding site81glycerol (UniProtKB | ChEBI)
Binding site81sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site82glycerol (UniProtKB | ChEBI)
Binding site82sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site133glycerol (UniProtKB | ChEBI)
Binding site133sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site242glycerol (UniProtKB | ChEBI)
Binding site242sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site243glycerol (UniProtKB | ChEBI)
Binding site264ADP (UniProtKB | ChEBI)
Binding site264ATP (UniProtKB | ChEBI)
Binding site309ADP (UniProtKB | ChEBI)
Binding site309ATP (UniProtKB | ChEBI)
Binding site313ATP (UniProtKB | ChEBI)
Binding site414ADP (UniProtKB | ChEBI)
Binding site414ATP (UniProtKB | ChEBI)
Binding site418ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol metabolic process
Biological Processglycerol-3-phosphate metabolic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • Ordered locus names
      Mpe_A3665

Organism names

Accessions

  • Primary accession
    A2SM29

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000987441-499Glycerol kinase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the FGGY kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    499
  • Mass (Da)
    53,229
  • Last updated
    2007-03-06 v1
  • Checksum
    A4B8980F6A9DF1AD
MTYLLALDQGTSSSRSIVFDRGGRIRAMAQREFRQLYPQPGWVEHDPMEIWETQLATAREALAQAGLTASDIAAIGITNQRETTLLWERASGRPIANAIVWQDRRTEPLCARWREQGLADAVRDVTGLVIDPYFSASKIAWLLDHVPGARTRAERGELAFGTVDSWLLRQLTGGRVHATDTTNASRTMLFDIDRGAWSEPLLAALDIPRALLPAVQQSASHFGDTEPALLGHAVPVCGIAGDQQAALFGQAGFQAGLAKNTYGTGCFLLMHTGAQRQASTHGLITTAAAQVDSTAPRQYALEGSVFIGGAVVQWLRDGLHAIRGSGEVQALAESVPDAGGVVVVPAFTGLGAPYWRPEASGAIVGLTRGSTVAHIARAALESIAFQSAALLDAMSRDAVAAGGQPVSELRVDGGACVNDLLMQFQADLLGIPVVRPQVIETTALGAACLAGLGCGLYAGTDELAAQWQAERRFLPTMPRERAAERMARWERAVRQTVAP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000555
EMBL· GenBank· DDBJ
ABM96618.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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