A2SJF0 · A2SJF0_METPP

Function

function

Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.
Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site69S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site90S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site116-117S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
Molecular Functiondemethylmenaquinone methyltransferase activity
Molecular FunctionS-adenosylmethionine:2-demethylmenaquinol methyltransferase activity
Molecular FunctionS-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity
Molecular FunctionS-adenosylmethionine:2-demethylquinol-8 methyltransferase activity
Biological Processaerobic respiration
Biological Processmenaquinone biosynthetic process
Biological Processmethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
  • EC number
  • Alternative names
    • 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase
    • Demethylmenaquinone methyltransferase

Gene names

    • Name
      ubiE
    • Ordered locus names
      Mpe_A2735

Organism names

Accessions

  • Primary accession
    A2SJF0

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    243
  • Mass (Da)
    26,635
  • Last updated
    2007-03-06 v1
  • Checksum
    00686A1A58251D09
MGSTHFGFQNVDEKEKAGRVRGVFDAVASKYDVMNDLMSLGLHRAWKAYTVAVANVRDGDRVLDIAGGTGDLARAFSRRVGSRGMVVHTDINEAMLRTGRDRLLDEGLVLPTAICDAEHLPFASGSFDVVSVAFGLRNMTHKEQALAEMARVLKPGGRLLVLEFSKVAKPLEKAYDWYSFQVLPRLGKWVANDADSYRYLAESIRMHPDQATLKSMMKAAGFGHVDVHNMAGGVVALHAGIRC

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000555
EMBL· GenBank· DDBJ
ABM95689.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp