A2SH88 · A2SH88_METPP

Function

function

Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

Catalytic activity

Pathway

Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.

Features

Showing features for active site.

136550100150200250300350
TypeIDPosition(s)Description
Active site247Proton acceptor

GO annotations

AspectTerm
Molecular FunctionN-acyltransferase activity
Biological Processlipid A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-3-O-acylglucosamine N-acyltransferase
  • EC number

Gene names

    • Name
      lpxD
    • Ordered locus names
      Mpe_A1969

Organism names

Accessions

  • Primary accession
    A2SH88

Proteomes

Interaction

Subunit

Homotrimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain26-94UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Region342-365Disordered

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxD subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    365
  • Mass (Da)
    37,353
  • Last updated
    2007-03-06 v1
  • Checksum
    C190DF648D2FE32C
MIDSAEVTLGDIAAALGGELIGPKSLDIARIGPLEDADAATISFLANPRYRAQLAGSSAGCVIVAPALRDEAVARGAAIVTPDPYLYFARLTQWWARRVRPAAVTGVHPSAVVDPGARLGAGVSIGALAVVEAGAQIDDGAEIGAQCFVGRAARVGAGTRLHPRVTLAFECVVGARCIVHSGAVIGADGFGFAPSREHGYVKIEQLGAVRIGDDVEIGANTCIDRGALGDTVIEDGVKLDNLIQIAHNVRIGRGTAMAAFTGVAGSTRIGEGCTFGGGAGVVGHVSIADGVHVSAHTAVLRSIDKPGVYTGIFPLAENRAWEKTAVTLRQLPALRERIRALERQAAAASDQEPGAADANGAENTP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000555
EMBL· GenBank· DDBJ
ABM94927.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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