A2SE78 · A2SE78_METPP
- ProteinAlcohol dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids711 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 Ca2+ ion per subunit.
Note: Binds 1 heme c group per subunit.
Note: Binds 1 PQQ group per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 146 | pyrroloquinoline quinone (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 208 | Ca2+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 285 | Ca2+ (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Active site | 330 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 330 | Ca2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 359 | pyrroloquinoline quinone (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 419-420 | pyrroloquinoline quinone (UniProtKB | ChEBI) | ||||
Sequence: NW | ||||||
Binding site | 638 | heme c (UniProtKB | ChEBI); covalent | ||||
Sequence: C | ||||||
Binding site | 641 | heme c (UniProtKB | ChEBI); covalent | ||||
Sequence: C | ||||||
Binding site | 642 | Fe (UniProtKB | ChEBI) of heme c (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 680 | Fe (UniProtKB | ChEBI) of heme c (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: M |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | calcium ion binding | |
Molecular Function | electron transfer activity | |
Molecular Function | heme binding | |
Molecular Function | oxidoreductase activity, acting on CH-OH group of donors |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Sphaerotilaceae > Methylibium
Accessions
- Primary accessionA2SE78
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-33 | |||||
Sequence: MHRRPAPSPAALVARLVVTLSLACGLSAPSAAA | ||||||
Chain | PRO_5002645750 | 34-711 | ||||
Sequence: GTEVNDAALSDPKQGANWLAYGRNYSEQRYSPLAQVHAGNVGRLGLAWSMALPEDRSLLSTPLIVDGVMYFTGSWSKTRAVDAATGKLLWEYDPESIKHAGGERLRAMWDSSRGLAYWKGKLVIATIDGRLIGLDAKTGQKLWSTQTFDPKRPLYISGHPKAFRDLVIVGNGGSEFGAGRGFVSAYHVDSGKLAWKFYVVPGNPADGFEDEAQAMAAKTWTGEWWKHGGGGQVWNGLTYDPEYDQILIGTGNGGPWNRKVRSPDGGDNLFLCSIVALDARTGKYKWHYQTVPGETWDYNSSMDMVLADLKLRPGGGPRKVLLHAPKNGFFYVIDRKNGKLLSAEKIAKVTWATGIDMKTGRPIEAEGARYEDGSELVWPSVYGAHNWHAMSFNPKTGLVYIPKVELPALFTDTGVRIVDWRKPENFGQLDVAVDIGLGSDIPKDAGVSSLLAWDPVKQKKAWEVAQPNYWNPGTMTTAGNLVFQGRIDGTFIAYDARDGRQLWSVHVGSGISAPPVTYSVGGRQYVSLLVGWGGAGMSLGGGSSMAQYGWGFGGQTRQLLTFALDGKLPMPDVGKPVFVRPIVPADFKPDEKLVDRGRALYASTCVWCHSAGAVSGGYAPDLRASPMLLDLKALRTVLEGALVQRGMPKYPDLTDDDLVALQHYVRSQAIVTSQPTPP |
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 625-702 | Cytochrome c | ||||
Sequence: KLVDRGRALYASTCVWCHSAGAVSGGYAPDLRASPMLLDLKALRTVLEGALVQRGMPKYPDLTDDDLVALQHYVRSQA |
Sequence similarities
Belongs to the bacterial PQQ dehydrogenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length711
- Mass (Da)77,099
- Last updated2007-03-06 v1
- ChecksumC4CC93068CE21F48
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000555 EMBL· GenBank· DDBJ | ABM93867.1 EMBL· GenBank· DDBJ | Genomic DNA |