A2SE78 · A2SE78_METPP

Function

Cofactor

Protein has several cofactor binding sites:
Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.
heme c (UniProtKB | Rhea| CHEBI:61717 )

Note: Binds 1 heme c group per subunit.
pyrroloquinoline quinone (UniProtKB | Rhea| CHEBI:58442 )

Note: Binds 1 PQQ group per subunit.

Features

Showing features for binding site, active site.

1711100200300400500600700
TypeIDPosition(s)Description
Binding site146pyrroloquinoline quinone (UniProtKB | ChEBI)
Binding site208Ca2+ (UniProtKB | ChEBI)
Binding site285Ca2+ (UniProtKB | ChEBI)
Active site330Proton acceptor
Binding site330Ca2+ (UniProtKB | ChEBI)
Binding site359pyrroloquinoline quinone (UniProtKB | ChEBI)
Binding site419-420pyrroloquinoline quinone (UniProtKB | ChEBI)
Binding site638heme c (UniProtKB | ChEBI); covalent
Binding site641heme c (UniProtKB | ChEBI); covalent
Binding site642Fe (UniProtKB | ChEBI) of heme c (UniProtKB | ChEBI); axial binding residue
Binding site680Fe (UniProtKB | ChEBI) of heme c (UniProtKB | ChEBI); axial binding residue

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functioncalcium ion binding
Molecular Functionelectron transfer activity
Molecular Functionheme binding
Molecular Functionoxidoreductase activity, acting on CH-OH group of donors

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Alcohol dehydrogenase
      (EC:1.-.-.-
      )

Gene names

    • Ordered locus names
      Mpe_A0905

Organism names

Accessions

  • Primary accession
    A2SE78

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-33
ChainPRO_500264575034-711

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain625-702Cytochrome c

Sequence similarities

Belongs to the bacterial PQQ dehydrogenase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    711
  • Mass (Da)
    77,099
  • Last updated
    2007-03-06 v1
  • Checksum
    C4CC93068CE21F48
MHRRPAPSPAALVARLVVTLSLACGLSAPSAAAGTEVNDAALSDPKQGANWLAYGRNYSEQRYSPLAQVHAGNVGRLGLAWSMALPEDRSLLSTPLIVDGVMYFTGSWSKTRAVDAATGKLLWEYDPESIKHAGGERLRAMWDSSRGLAYWKGKLVIATIDGRLIGLDAKTGQKLWSTQTFDPKRPLYISGHPKAFRDLVIVGNGGSEFGAGRGFVSAYHVDSGKLAWKFYVVPGNPADGFEDEAQAMAAKTWTGEWWKHGGGGQVWNGLTYDPEYDQILIGTGNGGPWNRKVRSPDGGDNLFLCSIVALDARTGKYKWHYQTVPGETWDYNSSMDMVLADLKLRPGGGPRKVLLHAPKNGFFYVIDRKNGKLLSAEKIAKVTWATGIDMKTGRPIEAEGARYEDGSELVWPSVYGAHNWHAMSFNPKTGLVYIPKVELPALFTDTGVRIVDWRKPENFGQLDVAVDIGLGSDIPKDAGVSSLLAWDPVKQKKAWEVAQPNYWNPGTMTTAGNLVFQGRIDGTFIAYDARDGRQLWSVHVGSGISAPPVTYSVGGRQYVSLLVGWGGAGMSLGGGSSMAQYGWGFGGQTRQLLTFALDGKLPMPDVGKPVFVRPIVPADFKPDEKLVDRGRALYASTCVWCHSAGAVSGGYAPDLRASPMLLDLKALRTVLEGALVQRGMPKYPDLTDDDLVALQHYVRSQAIVTSQPTPP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000555
EMBL· GenBank· DDBJ
ABM93867.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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