A2SE47 · A2SE47_METPP

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site244Mg2+ (UniProtKB | ChEBI)
Binding site274Mg2+ (UniProtKB | ChEBI)
Binding site276Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • Ordered locus names
      Mpe_A0874

Organism names

Accessions

  • Primary accession
    A2SE47

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain506-711Transketolase-like pyrimidine-binding

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    891
  • Mass (Da)
    97,498
  • Last updated
    2007-03-06 v1
  • Checksum
    C0B58909445D0E9C
MTQVFEPLLFQAAAADTDPAETAEWRDALAAVLAAAGPERARFLLDQLAAQASEPAIAWQPRGGGSPYVNTIPVERQPRFPGDLAIEERLASLMRWNALAMVVRANQAYGELGGHIASYASAADLFEVGFNHFFRARNAQQGGDLVFYQPHSAPGVYARAFLEGRLSEADLAHYRQELAAPAAGAQGLSSYPHPWLMPEFWQFPTGSMGIGPISSIYQARFMRYLQHRGLLQTEGRRVWGVFGDGEMDEPESMSALTLAAREKLDNLTWVINCNLQRLDGPVRGNGRIIDELEALFAGAGWQVIKLVWGSDWDGLFARDTHGALRKAFAGTVDGQFQTFAAKDGRYNREHFFGQTPELAALAQGLTDEQIDRLRRGGHDMVKIHAAYHAAMQCRGRPVVILAQTKKGYGMGEAGQGRMTTHQQKKLDRDDLIAFRNRFALPLSDEQAASLAFYKPADDSPEMRYLHARRAALGGQIPARVAQAPQLAVPPVARWGDFALNADGKEMSTTMAFVRMLTALLKDAQLGPRIVPIVADEARTFGMANLFKQIGIYSNLGQNYEPEDIGSVLSYREATDGQILEEGISEAGALSSWVAAATSYSVHGVPMLPFYIYYSMFGFQRVGDLIWAAADQRARGFLLGATAGRTTLGGEGLQHQDGSSPLQASTVPNCRTWDPAFAGEVAVIVEHGMRRMLEEQADEFFYLLLMNENYANPSLPEGAAAGVLKGLYRFRPAQGRKAAQVRLLGSGAILREVLAAAELLRNDYGVEAEVWSATSYSELQREAIEVERHNRLQPQAPRRRSHVAQCLAGKAPVVAASDYVRAWPQLIAPYAEASRFVALGTDGFGRSDTREQLRRHFEVDRAHIALAALDALADAGSVPREVAVKAAGRLAG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000555
EMBL· GenBank· DDBJ
ABM93836.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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