A2SCX9 · A2SCX9_METPP
- ProteinPeptidoglycan D,D-transpeptidase FtsI
- GeneftsI
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids607 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
Catalytic activity
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 327 | Acyl-ester intermediate | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | penicillin binding | |
Molecular Function | peptidoglycan glycosyltransferase activity | |
Molecular Function | serine-type D-Ala-D-Ala carboxypeptidase activity | |
Biological Process | cell wall organization | |
Biological Process | division septum assembly | |
Biological Process | FtsZ-dependent cytokinesis | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | proteolysis | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptidoglycan D,D-transpeptidase FtsI
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Sphaerotilaceae > Methylibium
Accessions
- Primary accessionA2SCX9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 52-70 | Helical | ||||
Sequence: FLVALVGAGFLLLLGRAVY |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 93-239 | Penicillin-binding protein dimerisation | ||||
Sequence: LPANRGRITDRGGELLASSVEAPTLWAIPRDVTATSAEKRQLARLLGMSVGDLEKRLADNPNFVYLRRQVDDSVALQVRALNLKGVHQLTEYKRRYPAGEAAAHVVGFTNVEDRGQEGIELAFQSDLAGRDGSRRVIKDRRGRVVED | ||||||
Domain | 280-576 | Penicillin-binding protein transpeptidase | ||||
Sequence: GSVVVLDVQSGEVLALANYPSYTPGDRRNLSGAQLRNRALTDTFEPGSTMKPFIIGEALQAGRVSPSTVIDTAPGRMSVTGSTISDAHPHGALTVEQVIQKSSNVGTVKISQLLSEREMWETFSAIGLGQKPQIDFPGAVTGRLRPYKTWRPIEKATMSYGYGLSASLFQLARAYTVFARDGELIPVSITRAQQPGAGVRVFSPEVARDVRHMLQMAAGPGGTGPKAQTIGYSVGGKSGTAHKQEGKGYADKKYRAWFVGLAPIDKPRIVVAVMVDEPNAGKYFGGEVAAPVFSEVV |
Sequence similarities
Belongs to the transpeptidase family. FtsI subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length607
- Mass (Da)65,809
- Last updated2007-03-06 v1
- ChecksumDC69AE106B1A2BCB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000555 EMBL· GenBank· DDBJ | ABM93418.1 EMBL· GenBank· DDBJ | Genomic DNA |