A2C604 · A2C604_PROM3
- ProteinFluoride-specific ion channel FluC
- GenefluC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids135 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Prochlorococcaceae > Prochlorococcus
Accessions
- Primary accessionA2C604
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-33 | Helical | ||||
Sequence: AWQASLVAIGAVPGAWLRLRVV | ||||||
Transmembrane | 45-65 | Helical | ||||
Sequence: WGTFAVNMVAAFALGLVLALQ | ||||||
Transmembrane | 77-100 | Helical | ||||
Sequence: LILLIGVGFFGSLSTFSTFAGEVL | ||||||
Transmembrane | 112-133 | Helical | ||||
Sequence: LVLAVGSILGGLLAVAAGVGLA |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length135
- Mass (Da)13,803
- Last updated2007-02-20 v1
- Checksum3E9CE0E61D1D9A5C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000554 EMBL· GenBank· DDBJ | ABM76914.1 EMBL· GenBank· DDBJ | Genomic DNA |