A2C027 · MURG_PROM1

  • Protein
    UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
  • Gene
    murG
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site11-13UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site120UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site161UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site188UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site286UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionUDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity
Molecular Functionundecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity
Biological Processcarbohydrate metabolic process
Biological Processcell division
Biological Processcell wall organization
Biological Processlipid glycosylation
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
  • EC number
  • Alternative names
    • Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Gene names

    • Name
      murG
    • Ordered locus names
      NATL1_02731

Organism names

Accessions

  • Primary accession
    A2C027

Proteomes

Subcellular Location

Cell inner membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003151421-352UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Structure

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    352
  • Mass (Da)
    38,959
  • Last updated
    2007-02-20 v1
  • Checksum
    0760B311D1CAC60B
MPRLLIAASGTGGHIYPALSFADSLSNSWEIVWLGVPNRLEVELVPEKYNLIKLKVGGLQGNIFRKLFDLCKLLFASVQVSVLLRQKKINVIFTTGGYISAPCILGAKMAGIPVLLHESNAIPGKVTRLLGRFCDHVALGIPSASEYLQRCRTSFTGTPVRTEFLFEKSLPSWVPLGEGVLIVVMGGSQGAIKMNEMVRKILPCLIEKGCRVVHLTGKNDCFYRNRDQEKSHPNLVVRDFSDEMPALLRNADLAISRSGAGAICELMVTKTPSILIPFPSSTDQHQELNAAYMARFGGAIIVNQHDPEKNILKNIVSNLLDSNSLREMKLNMNNHDYSYPEKKIFEIIHSIS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000553
EMBL· GenBank· DDBJ
ABM74837.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp