A2BWT5 · UPPP_PROM5
- ProteinUndecaprenyl-diphosphatase
- GeneuppP
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids266 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
Miscellaneous
Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
Catalytic activity
- di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + phosphate + H+
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | undecaprenyl-diphosphatase activity | |
Biological Process | cell wall organization | |
Biological Process | dephosphorylation | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape | |
Biological Process | response to antibiotic |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUndecaprenyl-diphosphatase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Prochlorococcaceae > Prochlorococcus
Accessions
- Primary accessionA2BWT5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1-21 | Helical | ||||
Sequence: MDFLKFIFYGIIQGLTEFIPV | ||||||
Transmembrane | 39-59 | Helical | ||||
Sequence: PGSSLSAIIQIGSVLAIFWYF | ||||||
Transmembrane | 86-106 | Helical | ||||
Sequence: SIFIGTIPIVLIGGIVKLFVT | ||||||
Transmembrane | 117-137 | Helical | ||||
Sequence: FSIAVVSILMSLIMFLADIST | ||||||
Transmembrane | 153-173 | Helical | ||||
Sequence: FIGISQAFAIIPGVSRSGATI | ||||||
Transmembrane | 190-210 | Helical | ||||
Sequence: SFLLGIPSISLAAFVEFITSI | ||||||
Transmembrane | 216-236 | Helical | ||||
Sequence: FPFLPLFVGLITTFFSSLLAI | ||||||
Transmembrane | 246-266 | Helical | ||||
Sequence: NGLKIFIYYRLVFGILIILNL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000290748 | 1-266 | Undecaprenyl-diphosphatase | |||
Sequence: MDFLKFIFYGIIQGLTEFIPVSSTAHLKIISQLFGVKDPGSSLSAIIQIGSVLAIFWYFRKYIFNTINSNSKILRPSFFSNKIYKSIFIGTIPIVLIGGIVKLFVTDFSNSFFRSNFSIAVVSILMSLIMFLADISTNKFINLSNHKYRNSLFIGISQAFAIIPGVSRSGATISMALLSGWDRKDAAKFSFLLGIPSISLAAFVEFITSINEFSTFPFLPLFVGLITTFFSSLLAIDFLLKYVSSNGLKIFIYYRLVFGILIILNL |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length266
- Mass (Da)29,709
- Last updated2007-02-20 v1
- Checksum4038DAF44225F63A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000552 EMBL· GenBank· DDBJ | ABM72246.1 EMBL· GenBank· DDBJ | Genomic DNA |