A2BWT5 · UPPP_PROM5

Function

function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionundecaprenyl-diphosphatase activity
Biological Processcell wall organization
Biological Processdephosphorylation
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-diphosphatase
  • EC number
  • Alternative names
    • Bacitracin resistance protein
    • Undecaprenyl pyrophosphate phosphatase

Gene names

    • Name
      uppP
    • Synonyms
      bacA
    • Ordered locus names
      P9515_10391

Organism names

Accessions

  • Primary accession
    A2BWT5

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane1-21Helical
Transmembrane39-59Helical
Transmembrane86-106Helical
Transmembrane117-137Helical
Transmembrane153-173Helical
Transmembrane190-210Helical
Transmembrane216-236Helical
Transmembrane246-266Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002907481-266Undecaprenyl-diphosphatase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the UppP family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    266
  • Mass (Da)
    29,709
  • Last updated
    2007-02-20 v1
  • Checksum
    4038DAF44225F63A
MDFLKFIFYGIIQGLTEFIPVSSTAHLKIISQLFGVKDPGSSLSAIIQIGSVLAIFWYFRKYIFNTINSNSKILRPSFFSNKIYKSIFIGTIPIVLIGGIVKLFVTDFSNSFFRSNFSIAVVSILMSLIMFLADISTNKFINLSNHKYRNSLFIGISQAFAIIPGVSRSGATISMALLSGWDRKDAAKFSFLLGIPSISLAAFVEFITSINEFSTFPFLPLFVGLITTFFSSLLAIDFLLKYVSSNGLKIFIYYRLVFGILIILNL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000552
EMBL· GenBank· DDBJ
ABM72246.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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