A2BID8 · A2BID8_DANRE

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendomembrane system
Cellular Componentmembrane
Molecular Functionheparin binding
Molecular Functionserine-type endopeptidase inhibitor activity
Molecular Functiontransition metal ion binding
Biological Processaxonogenesis
Biological Processcentral nervous system development

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Submitted names
    • Amyloid beta (A4) precursor-like protein 2
    • Amyloid-like protein 2 precursor
    • Aplp2 protein

Gene names

    • Name
      aplp2
    • Synonyms
      fk52a05
      , si:dkey-11k4.3
      , wu:fk52a05

Organism names

  • Taxonomic identifier
  • Strain
    • Tuebingen
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A2BID8
  • Secondary accessions
    • B1H1H1

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane695-717Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_503503487521-764
Disulfide bond45↔69
Disulfide bond80↔124
Disulfide bond105↔112
Disulfide bond140↔194
Disulfide bond151↔181
Disulfide bond165↔193

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain, compositional bias, coiled coil.

TypeIDPosition(s)Description
Region35-130GFLD subdomain
Domain35-196E1
Region138-196CuBD subdomain
Region196-307Disordered
Compositional bias211-245Acidic residues
Compositional bias254-285Acidic residues
Compositional bias286-307Basic and acidic residues
Domain315-365BPTI/Kunitz inhibitor
Domain379-570E2
Coiled coil437-464

Sequence similarities

Belongs to the APP family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    764
  • Mass (Da)
    86,612
  • Last updated
    2007-07-10 v2
  • Checksum
    45E445DCDFD207BB
MGSVPAVSVLILAIAVPSLAGYIEALAANAGTGFAVAEPQVAMFCGKLNMHINIQTGRWEPDPSGSKTCVGTKEGVLQYCQEIYPELQITNVVEANQPVKIENWCKKDKKQCKGHAHIVVPYKCLVGEFVSDVLLVPEKCKFFHKERMDMCVSHQQWHGVAKEACSKGNMVLHSYGMLLPCGIDKFHGTEYVCCPSTRPEEPAPPASPSKEMDDEDDDDEEEEDVEEPVVEEDEEDDEDAVDESEPVAIDPPTQEDTAEEEEEQEEDGDEEDYHYIYEDEEEDRDSEEKDVKKEKAVMPEKQDDDKTLQEVEAVCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMVVCKRLTVPPTPQPTDDVDVYFETPADDKEHSRFQKAKEQLEIRHRNRMERVRKEWEEAESQARNLPKAERQTLIQHFQAMVESLEEEAASEKQQLVETHLARVEAMLNDRRRLALENYLAALQADPPRPHRILQALKRYVRAENKDRQHTIRHYQHVLAVDPEKAAQMKSQVMTHLRVIEERMNQSLSLLYKVPYVAEEIQDEIDELLQVQKADMDQFLSSISESQPDVTVSSEESVEVPAFEGKPFRPFQVNSLGSPAEPEGSGMNSLDGLIGAEEKVINSKNKINENVVIDETLDVKEVILNGVDPLFSRGSEQESFRPLVDDFSFGSSALIGLLVIAVAIATVIVISLVLLRKRQYGTISHGIVEVDPMLTPEERHLSKMQNHGYENPTYKYLEQMQI

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2R8Q4V0A0A2R8Q4V0_DANREaplp2776
A0A8M9P166A0A8M9P166_DANREaplp2757
A0A8M9PA77A0A8M9PA77_DANREaplp2745
A0A8M9PFK9A0A8M9PFK9_DANREaplp2720

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias211-245Acidic residues
Compositional bias254-285Acidic residues
Compositional bias286-307Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX908399
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CT573112
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BC160603
EMBL· GenBank· DDBJ
AAI60603.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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