A2BDR7 · CF157_DANRE
- ProteinCilia- and flagella-associated protein 157
- Genecfap157
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids471 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | ciliary basal body | |
Cellular Component | cytoplasm | |
Molecular Function | microtubule binding | |
Biological Process | sperm axoneme assembly |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCilia- and flagella-associated protein 157
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionA2BDR7
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000307227 | 1-471 | Cilia- and flagella-associated protein 157 | |||
Sequence: MPPKKNGKKNRDQAIKTGGMEETEQKNAEELTESDKKFYQAQIRDLEERLERYQLKCDELEVQEKDLSSKINNVEKEKKDIVLFLKRTLAKKEDKLNDLAETLSRHQQAQEAERESFESQLSLLRRELQENKEKYTSENMTLAGKLASLEEFSTQRETLIAERRSLEEQLRKQKEDHQAEIYNLEKKAVLDNDRLKKEMLQHVATVAAEFRRVSDEKMPETTLRAMQENLSVTAQLQQLSEKTKELLKENDALRARERQLKRENGITEPLLHEITKKSVANQKVVLQLTEKCKQMQSEVEKCTKLKQDHQELLDIHSAVCTEIEDLRKKHAAVTEDLNQTKAEVERQKKELEEESRMRAQINTVLEEAAVALKEALRDVPEEEDSELKVTVRRSQMMQKLLAVLDGAAALGKGPALTDLMTCRPGALQKTSPHLSHYKTGDLGLVPRKTHSTSTKMGNLSRSAYTSLQKKA |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-33 | Disordered | ||||
Sequence: MPPKKNGKKNRDQAIKTGGMEETEQKNAEELTE | ||||||
Coiled coil | 27-190 | |||||
Sequence: NAEELTESDKKFYQAQIRDLEERLERYQLKCDELEVQEKDLSSKINNVEKEKKDIVLFLKRTLAKKEDKLNDLAETLSRHQQAQEAERESFESQLSLLRRELQENKEKYTSENMTLAGKLASLEEFSTQRETLIAERRSLEEQLRKQKEDHQAEIYNLEKKAVL | ||||||
Coiled coil | 225-369 | |||||
Sequence: AMQENLSVTAQLQQLSEKTKELLKENDALRARERQLKRENGITEPLLHEITKKSVANQKVVLQLTEKCKQMQSEVEKCTKLKQDHQELLDIHSAVCTEIEDLRKKHAAVTEDLNQTKAEVERQKKELEEESRMRAQINTVLEEAA | ||||||
Region | 447-471 | Disordered | ||||
Sequence: RKTHSTSTKMGNLSRSAYTSLQKKA |
Sequence similarities
Belongs to the CFAP157 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length471
- Mass (Da)54,196
- Last updated2007-02-20 v1
- Checksum5DFE6BD4E78E1ED3
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 19 | in Ref. 2; AAI21716 | ||||
Sequence: G → N | ||||||
Sequence conflict | 40 | in Ref. 2; AAI21716 | ||||
Sequence: Q → R | ||||||
Sequence conflict | 50 | in Ref. 2; AAI21716 | ||||
Sequence: L → P | ||||||
Sequence conflict | 205 | in Ref. 2; AAI21716 | ||||
Sequence: T → A | ||||||
Sequence conflict | 221 | in Ref. 2; AAI21716 | ||||
Sequence: T → M | ||||||
Sequence conflict | 245 | in Ref. 2; AAI21716 | ||||
Sequence: E → K | ||||||
Sequence conflict | 265 | in Ref. 2; AAI21716 | ||||
Sequence: G → D | ||||||
Sequence conflict | 274 | in Ref. 2; AAI21716 | ||||
Sequence: I → M | ||||||
Sequence conflict | 362 | in Ref. 2; AAI21716 | ||||
Sequence: N → S | ||||||
Sequence conflict | 370 | in Ref. 2; AAI21716 | ||||
Sequence: V → A | ||||||
Sequence conflict | 385 | in Ref. 2; AAI21716 | ||||
Sequence: S → C | ||||||
Sequence conflict | 419 | in Ref. 2; AAI21716 | ||||
Sequence: L → F | ||||||
Sequence conflict | 432 | in Ref. 2; AAI21716 | ||||
Sequence: P → S |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX001023 EMBL· GenBank· DDBJ | CAM14089.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC115176 EMBL· GenBank· DDBJ | AAI15177.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
BC121715 EMBL· GenBank· DDBJ | AAI21716.1 EMBL· GenBank· DDBJ | mRNA | Different initiation |