Activation of STING in pancreatic cancer-associated fibroblasts exerts an antitumor effect by enhancing tumor immunity.Suzuki Y., Sato T., Sugimori M., Kanemaru Y., Onodera S., Tsuchiya H., Nakamori Y., Tsuyuki S., Ikeda A.[...], Maeda S.View abstractSourceMGI: 1328312PubMedEurope PMCSci Rep 14:17071-17071 (2024)Mapped to31
Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.Bermejo-Rodriguez C., Araos Henriquez J., Caligiuri G., Pinto Teles S., Park Y., Evans A., Barrera L.N., Neesse A., Grutzmann R.[...], Perez-Mancera P.A.View abstractSourceMGI: 1328312PubMedEurope PMCCancer Res 84:2968-2984 (2024)Mapped to27
Oncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth.Donahue K.L., Watkoske H.R., Kadiyala P., Du W., Brown K., Scales M.K., Elhossiny A.M., Espinoza C.E., Lasse Opsahl E.L.[...], Pasca di Magliano M.View abstractSourceMGI: 1328312PubMedEurope PMCCancer Discov 14:1964-1989 (2024)Mapped to42
<i>Ehmt2</i> inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas.Pollin G., Mathison A.J., de Assuncao T.M., Thomas A., Zeighami A., Salmonson A., Liu H., Urrutia G., Vankayala P.[...], Lomberk G.View abstractSourceMGI: 1328312PubMedEurope PMCFront Genet 15:1412767-1412767 (2024)Mapped to9
Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression.Park J.H., Mortaja M., Son H.G., Zhao X., Sloat L.M., Azin M., Wang J., Collier M.R., Tummala K.S.[...], Demehri S.View abstractSourceMGI: 1328312PubMedEurope PMCNat Commun 15:4099-4099 (2024)Mapped to43
Tools for <i>Cre</i>-Mediated Conditional Deletion of Floxed Alleles from Developing Cerebellar Purkinje Cells.Jahncke J.N., Wright K.M.View abstractSourceMGI: 1328312PubMedEurope PMCeNeuro 11:ENEURO.0149-24.2024 (2024)Mapped to14
Msx genes delineate a novel molecular map of the developing cerebellar neuroepithelium.Gupta I., Yeung J., Rahimi-Balaei M., Wu S.R., Goldowitz D.View abstractSourceMGI: 1328312PubMedEurope PMCFront Mol Neurosci 17:1356544-1356544 (2024)Mapped to22
Cytokine CCL9 Mediates Oncogenic KRAS-Induced Pancreatic Acinar-to-Ductal Metaplasia by Promoting Reactive Oxygen Species and Metalloproteinases.Liou G.Y., Byrd C.J., Storz P., Messex J.K.View abstractSourceMGI: 1328312PubMedEurope PMCInt J Mol Sci 25:4726-4726 (2024)Mapped to9
Activin A signaling stimulates neutrophil activation and macrophage migration in pancreatitis.Wiley M.B., Bauer J., Alvarez V., Mehrotra K., Cheng W., Kolics Z., Giarrizzo M., Ingle K., Bialkowska A.B., Jung B.View abstractSourceMGI: 1328312PubMedEurope PMCSci Rep 14:9382-9382 (2024)Mapped to9
Childhood cancer mutagenesis caused by transposase-derived PGBD5.Yamada M., Keller R.R., Gutierrez R.L., Cameron D., Suzuki H., Sanghrajka R., Vaynshteyn J., Gerwin J., Maura F.[...], Kentsis A.View abstractSourceMGI: 1328312PubMedEurope PMCSci Adv 10:eadn4649-eadn4649 (2024)Mapped to19
Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation.Dewa K.I., Arimura N., Kakegawa W., Itoh M., Adachi T., Miyashita S., Inoue Y.U., Hizawa K., Hori K.[...], Hoshino M.View abstractSourceMGI: 1328312PubMedEurope PMCNat Commun 15:458-458 (2024)Mapped to6
Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.He B., Stoffel L., He C.J., Cho K., Li A.M., Jiang H., Flowers B.M., Nguyen K.T., Wang K.W.[...], Ye J.View abstractSourceMGI: 1328312PubMedEurope PMCCell Death Dis 15:89-89 (2024)Mapped to23
Semaphorin 6A in Retinal Ganglion Cells Regulates Functional Specialization of the Inner Retina.James R.E., Hamilton N.R., Huffman L.N., Pasterkamp J., Goff L.A., Kolodkin A.L.View abstractSourceMGI: 1328312PubMedEurope PMCbioRxiv 0:2023.11.18.567662-2023.11.18.567662 (2023)Mapped to26
Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation.Zhang A.M.Y., Xia Y.H., Lin J.S.H., Chu K.H., Wang W.C.K., Ruiter T.J.J., Yang J.C.C., Chen N., Chhuor J.[...], Kopp J.L.View abstractSourceMGI: 1328312PubMedEurope PMCCell Metab 35:2119-2135.e5 (2023)Mapped to16
Abnormal outer hair cell efferent innervation in Hoxb1-dependent sensorineural hearing loss.Di Bonito M., Bourien J., Tizzano M., Harrus A.G., Puel J.L., Avallone B., Nouvian R., Studer M.View abstractSourceMGI: 1328312PubMedEurope PMCPLoS Genet 19:e1010933-e1010933 (2023)Mapped to11
SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression.Bastos N., Castaldo S.A., Adem B., Machado J.C., Melo C.A., Melo S.A.View abstractSourceMGI: 1328312PubMedEurope PMCJ Transl Med 21:578-578 (2023)Mapped to49
Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8<sup>+</sup> T cells.Mahadevan K.K., LeBleu V.S., Ramirez E.V., Chen Y., Li B., Sockwell A.M., Gagea M., Sugimoto H., Sthanam L.K.[...], Kalluri R.View abstractSourceMGI: 1328312PubMedEurope PMCDev Cell 58:1562-1577.e8 (2023)Mapped to35
Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development.Guccini I., Tang G., To T.T., Di Rito L., Le Blanc S., Strobel O., D'Ambrosio M., Pasquini E., Bolis M.[...], Stoffel M.View abstractSourceMGI: 1328312PubMedEurope PMCiScience 26:107368-107368 (2023)Mapped to29
Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.Frank K.J., Mulero-Sanchez A., Berninger A., Ruiz-Canas L., Bosma A., Gorgulu K., Wu N., Diakopoulos K.N., Kaya-Aksoy E.[...], Mainardi S.View abstractSourceMGI: 1328312PubMedEurope PMCCell Rep Med 3:100815-100815 (2022)Mapped to23
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.Kerk S.A., Lin L., Myers A.L., Sutton D.J., Andren A., Sajjakulnukit P., Zhang L., Zhang Y., Jimenez J.A.[...], Lyssiotis C.A.View abstractSourceMGI: 1328312PubMedEurope PMCElife 11:e73245-e73245 (2022)Mapped to10
Dendritic Inhibition by Shh Signaling-Dependent Stellate Cell Pool Is Critical for Motor Learning.Li W., Chen L., Fleming J.T., Brignola E., Zavalin K., Lagrange A., Rex T., Heiney S.A., Wojaczynski G.J.[...], Chiang C.View abstractSourceMGI: 1328312PubMedEurope PMCJ Neurosci 42:5130-5143 (2022)Mapped to14
Acinar transformed ductal cells exhibit differential mucin expression in a tamoxifen-induced pancreatic ductal adenocarcinoma mouse model.Mallya K., Haridas D., Seshacharyulu P., Pothuraju R., Junker W.M., Krishn S.R., Muniyan S., Vengoji R., Batra S.K., Rachagani S.View abstractSourceMGI: 1328312PubMedEurope PMCBiol Open 9:bio052878-bio052878 (2020)Mapped to9
Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation.Brubaker D.K., Paulo J.A., Sheth S., Poulin E.J., Popow O., Joughin B.A., Strasser S.D., Starchenko A., Gygi S.P.[...], Haigis K.M.View abstractSourceMGI: 1328312PubMedEurope PMCCell Syst 9:258-270.e6 (2019)Mapped to2
The protective effect of betacellulin against acute pancreatitis is ERBB4 dependent.Hedegger K., Stumpf F., Blum H., Graf A., Schmid R.M., Lesina M., Algul H., Schneider M.R., Dahlhoff M.View abstractSourceMGI: 1328312PubMedEurope PMCJ Gastroenterol 55:317-329 (2020)Mapped to11
Corticospinal Circuits from the Sensory and Motor Cortices Differentially Regulate Skilled Movements through Distinct Spinal Interneurons.Ueno M., Nakamura Y., Li J., Gu Z., Niehaus J., Maezawa M., Crone S.A., Goulding M., Baccei M.L., Yoshida Y.View abstractSourceMGI: 1328312PubMedEurope PMCCell Rep 23:1286-1300.e7 (2018)Mapped to23