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A2AMS3 · A2AMS3_MOUSE

  • Protein
    Galactose-1-phosphate uridylyltransferase
  • Gene
    Galt
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Fe cation (UniProtKB | Rhea| CHEBI:24875 )

Note: Binds 1 Fe cation per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Pathway

Carbohydrate metabolism; galactose metabolism.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site29-32UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners
Binding site62UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners; in other chain
Binding site78-79UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners; in other chain
Binding site154UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners; in other chain
Binding site160-162UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners; in other chain
Active site167Tele-UMP-histidine intermediate
Binding site169UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners; in other chain
Binding site183Fe cation (UniProtKB | ChEBI)
Binding site282Fe cation (UniProtKB | ChEBI)
Binding site300Fe cation (UniProtKB | ChEBI)
Binding site302Fe cation (UniProtKB | ChEBI)
Binding site315-316UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners
Binding site320-321UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners
Binding site327UDP-alpha-D-glucose (UniProtKB | ChEBI); ligand shared between dimeric partners; in other chain

GO annotations

AspectTerm
Cellular ComponentGolgi apparatus
Molecular FunctionUDP-glucose:hexose-1-phosphate uridylyltransferase activity
Molecular Functionzinc ion binding
Biological Processgalactose metabolic process
Biological ProcessUDP-glucose metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Galactose-1-phosphate uridylyltransferase
  • EC number

Gene names

    • Name
      Galt

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    A2AMS3

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-177Galactose-1-phosphate uridyl transferase N-terminal
Domain184-349Galactose-1-phosphate uridyl transferase C-terminal

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    360
  • Mass (Da)
    41,235
  • Last updated
    2022-12-14 v3
  • MD5 Checksum
    88D5E77D410989C4D5D52B35BE95C919
MAATFRASEHQHIRYNPLQDEWVLVSAHRMKRPWQGQVEPQLLKTVPRHDPLNPLCPGATRANGEVNPHYDGTFLFDNDFPALQPDAPDPGPSDHPLFRAEAARGVCKVMCFHPWSDVTLPLMSVPEIRAVIDAWASVTEELGAQYPWVQIFENKGAMMGCSNPHPHCQVWASSFLPDIAQREERSQQTYHSQHGKPLLLEYGHQELLRKERLVLTSEHWIVLVPFWAVWPFQTLLLPRRHVRRLPELNPAERDDLASIMKKLLTKYDNLFETSFPYSMGWHGAPTGLKTGATCDHWQLHAHYYPPLLRSATVRKFMVGYEMLAQAQRDLTPEQAAERLRALPEVHYCLAQKDKETAAIA

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q03249GALT_MOUSEGalt379
Q3TQJ2Q3TQJ2_MOUSEGalt203
A2AMS2A2AMS2_MOUSEGalt356
A0A8V5L185A0A8V5L185_MOUSEGalt188
A0A8V5L0N9A0A8V5L0N9_MOUSEGalt225
A0A8V5KY85A0A8V5KY85_MOUSEGalt36
A0A8V5KX58A0A8V5KX58_MOUSEGalt65
A0A8V5KX60A0A8V5KX60_MOUSEGalt173

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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