ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.[...], Elledge S.J.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCScience 316:1160-1166 (2007)Cited in99+99+Mapped to23
Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons.Ding M., Qing X., Zhang G., Baade-Buttner C., Gruber R., Lu H., Ferguson D.O., Geis C., Wang Z.Q., Zhou Z.W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1351625PubMedEurope PMCFront Aging Neurosci 13:786199-786199 (2021)Mapped to10
Nbs1-mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis.Chen Y., Sun J., Ju Z., Wang Z.Q., Li T.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCCell Prolif 54:e12972-e12972 (2021)Mapped to40
The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.Dar A.A., Sawada K., Dybas J.M., Moser E.K., Lewis E.L., Park E., Fazelinia H., Spruce L.A., Ding H.[...], Oliver P.M.View abstractSourceMGI: 1351625PubMedEurope PMCPLoS Biol 19:e3001041-e3001041 (2021)Mapped to46
NBS1 interacts with Notch signaling in neuronal homeostasis.Zhou Z.W., Kirtay M., Schneble N., Yakoub G., Ding M., Rudiger T., Siniuk K., Lu R., Jiang Y.N.[...], Wang Z.Q.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCNucleic Acids Res 48:10924-10939 (2020)Mapped to2
NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis.Zhang B., Tang Z., Li L., Lu L.Y.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCCell Death Differ 27:2176-2190 (2020)Mapped to4
Nbn-Mre11 interaction is required for tumor suppression and genomic integrity.Kim J.H., Penson A.V., Taylor B.S., Petrini J.H.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1351625PubMedEurope PMCProc Natl Acad Sci U S A 116:15178-15183 (2019)Mapped to16
CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs.Mohiuddin M., Rahman M.M., Sale J.E., Pearson C.E.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCNucleic Acids Res 47:2966-2980 (2019)Mapped to43
MRI is a DNA damage response adaptor during classical non-homologous end joining.Hung P.J., Johnson B., Chen B.R., Byrum A.K., Bredemeyer A.L., Yewdell W.T., Johnson T.E., Lee B.J., Deivasigamani S.[...], Sleckman B.P.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCMol. Cell 71:332-342 (2018)Cited in9Mapped to24
The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.Syed A., Tainer J.A.View abstractCategoriesFunction, InteractionSourceMGI: 1351625PubMedEurope PMCAnnu Rev Biochem 87:263-294 (2018)Mapped to36
MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene- Induced Replication Stress.Spehalski E., Capper K.M., Smith C.J., Morgan M.J., Dinkelmann M., Buis J., Sekiguchi J.M., Ferguson D.O.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCCancer Res 77:5327-5338 (2017)Mapped to35
NBS1 phosphorylation status dictates repair choice of dysfunctional telomeres.Rai R., Hu C., Broton C., Chen Y., Lei M., Chang S.View abstractCategoriesFunction, InteractionSourceMGI: 1351625PubMedEurope PMCMol. Cell 65:801-817 (2017)Cited in6Mapped to13
The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression.Kim J.H., Grosbart M., Anand R., Wyman C., Cejka P., Petrini J.H.J.View abstractCategoriesInteractionSourceMGI: 1351625PubMedEurope PMCCell Rep 18:496-507 (2017)Mapped to24
Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.Hoa N.N., Shimizu T., Zhou Z.W., Wang Z.Q., Deshpande R.A., Paull T.T., Akter S., Tsuda M., Furuta R.[...], Sasanuma H.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCMol Cell 64:580-592 (2016)Mapped to28
A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination.Rocha P.P., Raviram R., Fu Y., Kim J., Luo V.M., Aljoufi A., Swanzey E., Pasquarella A., Balestrini A.[...], Skok J.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1351625PubMedEurope PMCCell Rep 16:48-55 (2016)Mapped to56
Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis.Seidel P., Remus M., Delacher M., Grigaravicius P., Reuss D.E., Frappart L., von Deimling A., Feuerer M., Abdollahi A., Frappart P.O.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCOncotarget 7:23006-23018 (2016)Mapped to23
DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.Prochazkova J., Sakaguchi S., Owusu M., Mazouzi A., Wiedner M., Velimezi G., Moder M., Turchinovich G., Hladik A.[...], Loizou J.I.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCPLoS Genet 11:e1005645-e1005645 (2015)Mapped to22
Defining ATM-Independent Functions of the Mre11 Complex with a Novel Mouse Model.Balestrini A., Nicolas L., Yang-Lott K., Guryanova O.A., Levine R.L., Bassing C.H., Chaudhuri J., Petrini J.H.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCMol Cancer Res 14:185-195 (2016)Mapped to8
ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor.Lavin M.F., Kozlov S., Gatei M., Kijas A.W.View abstractCategoriesFunction, PTM / ProcessingSourceMGI: 1351625PubMedEurope PMCBiomolecules 5:2877-2902 (2015)Mapped to17
NBS1 is required for macrophage homeostasis and functional activity in mice.Pereira-Lopes S., Tur J., Calatayud-Subias J.A., Lloberas J., Stracker T.H., Celada A.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCBlood 126:2502-2510 (2015)Mapped to2
EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele.Rein K., Yanez D.A., Terre B., Palenzuela L., Aivio S., Wei K., Edelmann W., Stark J.M., Stracker T.H.View abstractCategoriesFunctionSourceMGI: 1351625PubMedEurope PMCNucleic Acids Res 43:7371-7387 (2015)Mapped to10