Cell death in development.Vaux D.L., Korsmeyer S.J.CategoriesFunctionSourceMGI: 88139PubMedEurope PMCCell 96:245-254 (1999)Mapped to50
Bcl-2 family proteins.Reed J.C.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCOncogene 17:3225-3236 (1998)Mapped to49
In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system.Srinivasan A., Roth K.A., Sayers R.O., Shindler K.S., Wong A.M., Fritz L.C., Tomaselli K.J.View abstractCategoriesFunction, InteractionSourceMGI: 88139PubMedEurope PMCCell Death Differ 5:1004-1016 (1998)Mapped to20
Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins.Chen G., Cizeau J., Vande Velde C., Park J.H., Bozek G., Bolton J., Shi L., Dubik D., Greenberg A.View abstractCategoriesSubcellular LocationSourceMGI: 88139PubMedEurope PMCJ. Biol. Chem. 274:7-10 (1999)Cited in3Mapped to15
Expression and regulation of genes associated with cell death during murine preimplantation embryo development.Jurisicova A., Latham K.E., Casper R.F., Casper R.F., Varmuza S.L.View abstractCategoriesExpressionSourceMGI: 88139PubMedEurope PMCMol Reprod Dev 51:243-253 (1998)Mapped to52
Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies.Packham G., White E.L., Eischen C.M., Yang H., Parganas E., Ihle J.N., Grillot D.A., Zambetti G.P., Nunez G., Cleveland J.L.View abstractCategoriesFunction, InteractionSourceMGI: 88139PubMedEurope PMCGenes Dev 12:2475-2487 (1998)Mapped to8
Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing.Fang W., Weintraub B.C., Dunlap B., Garside P., Pape K.A., Jenkins M.K., Goodnow C.C., Mueller D.L., Behrens T.W.View abstractCategoriesFunction, SequencesSourceMGI: 88139PubMedEurope PMCImmunity 9:35-45 (1998)Mapped to8
A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas.Pena J.C., Rudin C.M., Thompson C.B.View abstractCategoriesFunction, SequencesSourceMGI: 88139PubMedEurope PMCCancer Res 58:2111-2116 (1998)Mapped to8
Transgene expression of bcl-xL permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells.Solvason N., Wu W.W., Kabra N., Lund-Johansen F., Roncarolo M.G., Behrens T.W., Grillot D.A., Nunez G., Lees E., Howard M.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCJ Exp Med 187:1081-1091 (1998)Mapped to11
Blk, a BH3-containing mouse protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist.Hegde R., Srinivasula S.M., Ahmad M., Fernandes-Alnemri T., Alnemri E.S.View abstractCategoriesInteractionSourceMGI: 88139PubMedEurope PMCJ. Biol. Chem. 273:7783-7786 (1998)Cited in1Mapped to14
Bcl-X is the major pleiotropic anti-apoptotic gene activated by retroviral insertion mutagenesis in an IL-3 dependent bone marrow derived cell line.Thomas J., Leverrier Y., Marvel J.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCOncogene 16:1399-1408 (1998)Mapped to8
Bim: a novel member of the Bcl-2 family that promotes apoptosis.O'Connor L., Strasser A., O'Reilly L.A., Hausmann G., Adams J.M., Cory S., Huang D.C.S.View abstractCategoriesInteractionSourceMGI: 88139PubMedEurope PMCEMBO J. 17:384-395 (1998)Cited in2Mapped to17
A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells.Yang X.-F., Weber G.F., Cantor H.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCImmunity 7:629-639 (1997)Cited in11Mapped to6
Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.Kelekar A., Chang B.S., Harlan J.E., Fesik S.W., Thompson C.B.View abstractCategoriesInteractionSourceMGI: 88139PubMedEurope PMCMol Cell Biol 17:7040-7046 (1997)Mapped to15
Bcl-x protects primary B cells against Fas-mediated apoptosis.Schneider T.J., Grillot D., Foote L.C., Nunez G.E., Rothstein T.L.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCJ Immunol 159:4834-4839 (1997)Mapped to8
Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta.Moser M., Buettner R.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCGenes Dev. 11:1938-1948 (1997)Cited in1Mapped to74
Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation.Van Houten N., Blake S.F., Li E.J., Hallam T.A., Chilton D.G., Gourley W.K., Boise L.H., Thompson C.B., Thompson E.B.View abstractCategoriesFunction, InteractionSourceMGI: 88139PubMedEurope PMCInt Immunol 9:945-953 (1997)Mapped to19
Bcl-x expression influences keratinocyte cell survival but not terminal differentiation.Pena J.C., Fuchs E., Thompson C.B.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCCell Growth Differ 8:619-629 (1997)Mapped to8
The apoptosis and proliferation of SAC-activated B cells by IL-10 are associated with changes in Bcl-2, Bcl-xL, and Mcl-1 expression.Li L., Krajewski S., Reed J.C., Choi Y.S.View abstractCategoriesExpressionSourceMGI: 88139PubMedEurope PMCCell Immunol 178:33-41 (1997)Mapped to25
Expression of Bcl-2 family during liver regeneration and identification of Bcl-x as a delayed early response gene.Tzung S.P., Fausto N., Hockenbery D.M.View abstractCategoriesExpressionSourceMGI: 88139PubMedEurope PMCAm J Pathol 150:1985-1995 (1997)Mapped to31
Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene.Grillot D.A., Gonzalez-Garcia M., Ekhterae D., Duan L., Inohara N., Ohta S., Seldin M.F., Nunez G.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCJ. Immunol. 158:4750-4757 (1997)Cited in1Mapped to15
Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice.Shindler K.S., Latham C.B., Roth K.A.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCJ Neurosci 17:3112-3119 (1997)Mapped to17
Spontaneous overexpression of the long form of the Bcl-X protein in a highly resistant P388 leukaemia.Kuhl J.S., Krajewski S., Duran G.E., Reed J.C., Sikic B.I.View abstractCategoriesFunction, SequencesSourceMGI: 88139PubMedEurope PMCBr J Cancer 75:268-274 (1997)Mapped to8
A1 demonstrates restricted tissue distribution during embryonic development and functions to protect against cell death.Carrio R., Lopez-Hoyos M., Jimeno J., Benedict M.A., Merino R., Benito A., Fernandez-Luna J.L., Nunez G., Garcia-Porrero J.A., Merino J.View abstractCategoriesExpressionSourceMGI: 88139PubMedEurope PMCAm J Pathol 149:2133-2142 (1996)Mapped to11
Overexpression of Bcl-2 or Bcl-XL transgenes and photoreceptor degeneration.Joseph R.M., Li T.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCInvest Ophthalmol Vis Sci 37:2434-2446 (1996)Mapped to17
BID: a novel BH3 domain-only death agonist.Wang K., Yin X.-M., Chao D.T., Milliman C.L., Korsmeyer S.J.View abstractCategoriesInteractionSourceMGI: 88139PubMedEurope PMCGenes Dev. 10:2859-2869 (1996)Cited in2Mapped to21
Chromosomal assignment of the Bcl2-related genes, Bcl2l and Bax, in the mouse and rat.Matsuda Y., Kusano H., Tsujimoto Y.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCCytogenet Cell Genet 74:107-110 (1996)Mapped to17
Localization of bcl-2, bax, and bcl-x mRNAs in the developing inner ear of the mouse.Ishii N., Wanaka A., Ohno K., Matsumoto K., Eguchi Y., Mori T., Tsujimoto Y., Tohyama M.View abstractCategoriesSequences, ExpressionSourceMGI: 88139PubMedEurope PMCBrain Res 726:123-128 (1996)Mapped to20
The rise and fall of apoptosis during multistage tumorigenesis: down- modulation contributes to tumor progression from angiogenic progenitors.Naik P., Karrim J., Hanahan D.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCGenes Dev 10:2105-2116 (1996)Mapped to22
Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL.Simonian P.L., Grillot D.A., Merino R., Nunez G.View abstractCategoriesInteractionSourceMGI: 88139PubMedEurope PMCJ Biol Chem 271:22764-22772 (1996)Mapped to17
Bax and Bcl-xs are induced at the onset of apoptosis in involuting mammary epithelial cells.Heermeier K., Benedict M., Li M., Furth P., Nunez G., Hennighausen L.View abstractCategoriesExpressionSourceMGI: 88139PubMedEurope PMCMech Dev 56:197-207 (1996)Mapped to17
Role of bcl-X(L) in the control of apoptosis in murine myeloma cells.Gauthier E.R., Piche L., Lemieux G., Lemieux R.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCCancer Res 56:1451-1456 (1996)Mapped to8
bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.Grillot D.A., Merino R., Pena J.C., Fanslow W.C., Finkelman F.D., Thompson C.B., Nunez G.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCJ Exp Med 183:381-391 (1996)Mapped to8
Bcl-x(S) anatagonizes the protective effects of Bcl-x(L).Minn A.J., Boise L.H., Thompson C.B.View abstractCategoriesInteractionSourceMGI: 88139PubMedEurope PMCJ Biol Chem 271:6306-6312 (1996)Mapped to8
Bax promotes neuronal survival and antagonises the survival effects of neurotrophic factors.Middleton G., Nunez G., Davies A.M.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCDevelopment 122:695-701 (1996)Mapped to20
Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a bcl-xL transgene.Fang W., Mueller D.L., Pennell C.A., Rivard J.J., Li Y.S., Hardy R.R., Schlissel M.S., Behrens T.W.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCImmunity 4:291-299 (1996)Mapped to8
Expression of bcl-x during mouse B cell differentiation and following activation by various stimuli.Choi M.S., Holmann M., Atkins C.J., Klaus G.G.View abstractCategoriesExpressionSourceMGI: 88139PubMedEurope PMCEur J Immunol 26:676-682 (1996)Mapped to11
Molecular evolution and secondary structural conservation in the B-cell lymphoma leukemia 2 (bcl-2) family of proto-oncogene products.Evans D.L., Mansel R.E.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCJ Mol Evol 41:775-783 (1995)Mapped to14
Localization of the gene for the ciliary neurotrophic factor receptor (CNTFR) to human chromosome 9.Donaldson D.H., Britt D.E., Jones C., Jackson C.L., Patterson D.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCGenomics 17:782-784 (1993)Mapped to8
Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2.Swendeman S.L., Spielholz C., Jenkins N.A., Gilbert D.J., Copeland N.G., Sheffery M.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCJ. Biol. Chem. 269:11663-11671 (1994)Cited in1Mapped to41
Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes.Fang W., Rivard J.J., Mueller D.L., Behrens T.W.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCJ. Immunol. 153:4388-4398 (1994)Cited in1Mapped to7
Massive cell death of immature hematopoietic cells and neurons in Bcl-x- deficient mice.Motoyama N., Wang F., Roth K.A., Sawa H., Nakayama K., Nakayama K., Negishi I., Senju S., Zhang Q., Fujii S.View abstractCategoriesExpressionSourceMGI: 88139PubMedEurope PMCScience 267:1506-1510 (1995)Mapped to25
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death.Yang E., Zha J., Jockel J., Boise L.H., Thompson C.B., Korsmeyer S.J.View abstractCategoriesInteractionSourceMGI: 88139PubMedEurope PMCCell 80:285-291 (1995)Cited in1Mapped to32
Bclx regulates the survival of double-positive thymocytes.Ma A., Pena J.C., Chang B., Margosian E., Davidson L., Alt F.W., Thompson C.B.View abstractCategoriesFunction, ExpressionSourceMGI: 88139PubMedEurope PMCProc Natl Acad Sci U S A 92:4763-4767 (1995)Mapped to8
bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death.Gonzalez-Garcia M., Garcia I., Ding L., O'Shea S., Boise L.H., Thompson C.B., Nunez G.View abstractCategoriesSequences, ExpressionSourceMGI: 88139PubMedEurope PMCProc Natl Acad Sci U S A 92:4304-4308 (1995)Mapped to11
Presence of the long and the short forms of Bcl-X in several human and murine tissues.Rouayrenc J.F., Boise L.H., Thompson C.B., Privat A., Patey G.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCC R Acad Sci III 318:537-540 (1995)Mapped to8
Regulation of bcl-2, bcl-XL and bax in the control of apoptosis by hematopoietic cytokines and dexamethasone.Lotem J., Sachs L.View abstractCategoriesExpressionSourceMGI: 88139PubMedEurope PMCCell Growth Differ 6:647-653 (1995)Mapped to20
Bcl-XL and Bcl-2 repress a common pathway of cell death.Chao D.T., Linette G.P., Boise L.H., White L.S., Thompson C.B., Korsmeyer S.J.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCJ Exp Med 182:821-828 (1995)Mapped to20
Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal.Broome H.E., Dargan C.M., Krajewski S., Reed J.C.View abstractCategoriesFunctionSourceMGI: 88139PubMedEurope PMCJ Immunol 155:2311-2317 (1995)Mapped to20
bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria.Gonzalez-Garcia M., Perez-Ballestero R., Ding L., Duan L., Boise L.H., Thompson C.B., Nunez G.View abstractCategoriesSequencesSourceMGI: 88139PubMedEurope PMCDevelopment 120:3033-3042 (1994)Cited in1Mapped to10