A2A3E7 · A2A3E7_HUMAN
- ProteinProtocadherin related 15
- GenePCDH15
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1957 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | stereocilium | |
Molecular Function | calcium ion binding | |
Biological Process | homophilic cell adhesion via plasma membrane adhesion molecules | |
Biological Process | inner ear development | |
Biological Process | sensory perception of sound |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA2A3E7
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 1375-1397 | Helical | |||
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,960 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Genetic variation databases
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-26 | ||||
Chain | PRO_5002642602 | 27-1957 | |||
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 148-265 | Cadherin | |||
Domain | 278-395 | Cadherin | |||
Domain | 396-509 | Cadherin | |||
Domain | 510-616 | Cadherin | |||
Domain | 617-717 | Cadherin | |||
Domain | 719-819 | Cadherin | |||
Domain | 820-926 | Cadherin | |||
Domain | 927-1035 | Cadherin | |||
Domain | 1037-1144 | Cadherin | |||
Domain | 1145-1259 | Cadherin | |||
Region | 1426-1446 | Disordered | |||
Region | 1603-1624 | Disordered | |||
Region | 1747-1768 | Disordered | |||
Region | 1930-1957 | Disordered | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,957
- Mass (Da)216,339
- Last updated2008-02-05 v1
- ChecksumB8B0FC26DAD4B539
Computationally mapped potential isoform sequences
There are 22 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q96QU1 | PCD15_HUMAN | PCDH15 | 1955 | ||
A0A2R8Y6C0 | A0A2R8Y6C0_HUMAN | PCDH15 | 1740 | ||
A0A2R8YEV2 | A0A2R8YEV2_HUMAN | PCDH15 | 1360 | ||
B7ZBT8 | B7ZBT8_HUMAN | PCDH15 | 1150 | ||
E7EM53 | E7EM53_HUMAN | PCDH15 | 1886 | ||
E7EM97 | E7EM97_HUMAN | PCDH15 | 329 | ||
E7EMG8 | E7EMG8_HUMAN | PCDH15 | 654 | ||
A2A3D8 | A2A3D8_HUMAN | PCDH15 | 1962 | ||
A2A3D9 | A2A3D9_HUMAN | PCDH15 | 92 | ||
A2A3E1 | A2A3E1_HUMAN | PCDH15 | 650 | ||
A2A3E4 | A2A3E4_HUMAN | PCDH15 | 981 | ||
A2A3E5 | A2A3E5_HUMAN | PCDH15 | 719 | ||
A2A3E6 | A2A3E6_HUMAN | PCDH15 | 1952 | ||
A2A3E8 | A2A3E8_HUMAN | PCDH15 | 1932 | ||
A9Z1W1 | A9Z1W1_HUMAN | PCDH15 | 1677 | ||
A0A087X1T6 | A0A087X1T6_HUMAN | PCDH15 | 1682 | ||
A0A087WTR6 | A0A087WTR6_HUMAN | PCDH15 | 1539 | ||
A0A087WUC7 | A0A087WUC7_HUMAN | PCDH15 | 37 | ||
A0A087WX70 | A0A087WX70_HUMAN | PCDH15 | 416 | ||
A0A087WXQ6 | A0A087WXQ6_HUMAN | PCDH15 | 72 | ||
A0A087WZN4 | A0A087WZN4_HUMAN | PCDH15 | 460 | ||
A0A087WZN9 | A0A087WZN9_HUMAN | PCDH15 | 1790 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC013737 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC016817 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC024073 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC027671 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL353784 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL360214 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL365496 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL391356 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF455239 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |