A1ZBC7 · A1ZBC7_DROME
- ProteinTransporter
- GeneList
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids564 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | plasma membrane | |
Molecular Function | amino acid:monoatomic cation symporter activity | |
Molecular Function | amino acid:sodium symporter activity | |
Molecular Function | L-amino acid transmembrane transporter activity | |
Molecular Function | neurotransmitter transmembrane transporter activity | |
Biological Process | amino acid import across plasma membrane | |
Biological Process | amino acid transmembrane transport | |
Biological Process | neurotransmitter transport | |
Biological Process | response to lithium ion | |
Biological Process | sodium ion transmembrane transport |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTransporter
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionA1ZBC7
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 21-42 | Helical | ||||
Sequence: WGNGLEFLFSCISLSVGLGNIW | ||||||
Transmembrane | 54-74 | Helical | ||||
Sequence: GTFVIPYLIALLVIGRPVYYL | ||||||
Transmembrane | 95-126 | Helical | ||||
Sequence: LLKGVALGQVLATAASITYYSSIMALTLRFWL | ||||||
Transmembrane | 185-206 | Helical | ||||
Sequence: WQLVACLAIAWLVIGGVLIRGI | ||||||
Transmembrane | 218-245 | Helical | ||||
Sequence: VFPYVVLLILLLRAVTLPGAIDGIIYFF | ||||||
Transmembrane | 257-281 | Helical | ||||
Sequence: VWYAAVTQVFFSLAICFGTLITYAS | ||||||
Transmembrane | 293-315 | Helical | ||||
Sequence: IVIITTMDSCSSIIAGCITFGIL | ||||||
Transmembrane | 356-382 | Helical | ||||
Sequence: FAVLFFLMLFVLGIGSTVGMGSCILRV | ||||||
Transmembrane | 394-414 | Helical | ||||
Sequence: IWKLASGLTVLGFSVSIVYMT | ||||||
Transmembrane | 426-450 | Helical | ||||
Sequence: FYGVSFTALILAIGELVAVAWIYGV | ||||||
Transmembrane | 471-490 | Helical | ||||
Sequence: LCWRFITPGLMTAVLIYMLL | ||||||
Transmembrane | 505-530 | Helical | ||||
Sequence: LAHVFGCFLATLGLIQLPGWAIYAIY |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 138↔146 | |||||
Sequence: CWESWGTDC |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length564
- Mass (Da)62,187
- Last updated2010-11-30 v2
- Checksum650BE75263417FF3
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A1ZBC8 | A1ZBC8_DROME | List | 387 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE013599 EMBL· GenBank· DDBJ | AAF57648.3 EMBL· GenBank· DDBJ | Genomic DNA |