A1Z7Q1 · A1Z7Q1_DROME
- ProteinSuppressor of variegation 2-10, isoform B
- GeneSu(var)2-10
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids593 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
Pathway
Protein modification; protein sumoylation.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | chromatin | |
Cellular Component | nucleus | |
Molecular Function | SUMO ligase activity | |
Molecular Function | transcription coregulator activity | |
Molecular Function | zinc ion binding | |
Biological Process | compound eye development | |
Biological Process | defense response to Gram-negative bacterium | |
Biological Process | double-strand break repair via homologous recombination | |
Biological Process | imaginal disc growth | |
Biological Process | positive regulation of innate immune response | |
Biological Process | protein sumoylation | |
Biological Process | regulation of transcription by RNA polymerase II |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionA1Z7Q1
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-36 | SAP | ||||
Sequence: VQMLRVVELQKILSFLNISFAGRKTDLQSRILSFL | ||||||
Domain | 113-278 | PINIT | ||||
Sequence: HSINSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKL | ||||||
Domain | 310-391 | SP-RING-type | ||||
Sequence: ADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLL | ||||||
Compositional bias | 402-422 | Polar residues | ||||
Sequence: QDGSWSTPGLRSETQILDTPS | ||||||
Region | 402-547 | Disordered | ||||
Sequence: QDGSWSTPGLRSETQILDTPSKPAQKVEVISDDIELISDDAKPVKRDLSPAQDEQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVASSTSNGSGGGQRAYTPAQQPQQSESPEQQASRQSPEKQTVSEQQLQQQQHEQPATA | ||||||
Compositional bias | 429-450 | Basic and acidic residues | ||||
Sequence: EVISDDIELISDDAKPVKRDLS | ||||||
Compositional bias | 452-468 | Polar residues | ||||
Sequence: AQDEQPTSTSNSETVDL | ||||||
Compositional bias | 488-546 | Polar residues | ||||
Sequence: QAVASSTSNGSGGGQRAYTPAQQPQQSESPEQQASRQSPEKQTVSEQQLQQQQHEQPAT |
Sequence similarities
Belongs to the PIAS family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length593
- Mass (Da)65,210
- Last updated2007-02-06 v1
- ChecksumCA25E675AD87D873
Computationally mapped potential isoform sequences
There are 13 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A1Z7P5 | A1Z7P5_DROME | Su(var)2-10 | 640 | ||
A0A0B4JD33 | A0A0B4JD33_DROME | Su(var)2-10 | 584 | ||
A0A0B4JCQ7 | A0A0B4JCQ7_DROME | Su(var)2-10 | 537 | ||
A0A0B4JD03 | A0A0B4JD03_DROME | Su(var)2-10 | 537 | ||
A0A0B4K6T9 | A0A0B4K6T9_DROME | Su(var)2-10 | 570 | ||
Q5BIG7 | Q5BIG7_DROME | Su(var)2-10 | 533 | ||
Q7KNF5 | Q7KNF5_DROME | Su(var)2-10 | 554 | ||
A0A0B4LEH9 | A0A0B4LEH9_DROME | Su(var)2-10 | 577 | ||
Q9XYM5 | Q9XYM5_DROME | Su(var)2-10 | 522 | ||
A1Z7P7 | A1Z7P7_DROME | Su(var)2-10 | 569 | ||
A1Z7P8 | A1Z7P8_DROME | Su(var)2-10 | 604 | ||
A1Z7P9 | A1Z7P9_DROME | Su(var)2-10 | 565 | ||
Q8IGK3 | Q8IGK3_DROME | Su(var)2-10 | 601 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 402-422 | Polar residues | ||||
Sequence: QDGSWSTPGLRSETQILDTPS | ||||||
Compositional bias | 429-450 | Basic and acidic residues | ||||
Sequence: EVISDDIELISDDAKPVKRDLS | ||||||
Compositional bias | 452-468 | Polar residues | ||||
Sequence: AQDEQPTSTSNSETVDL | ||||||
Compositional bias | 488-546 | Polar residues | ||||
Sequence: QAVASSTSNGSGGGQRAYTPAQQPQQSESPEQQASRQSPEKQTVSEQQLQQQQHEQPAT |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE013599 EMBL· GenBank· DDBJ | AAG22293.1 EMBL· GenBank· DDBJ | Genomic DNA |