A1Z6X2 · A1Z6X2_DROME
- ProteinDown syndrome cell adhesion molecule 1, isoform E
- GeneDscam1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2022 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Keywords
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionA1Z6X2
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1625-1646 | Helical | ||||
Sequence: LVVPVVAALLVIIIAIIVICIL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-28 | |||||
Sequence: MNMPNERLKWLMLFAAVALIACGSQTLA | ||||||
Chain | PRO_5002641862 | 29-2022 | ||||
Sequence: ANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVAQYYDTDVNKAYVIRGNAAVLKCEIPSFVADFVSVVSWHTDQNEDFLPGSEYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGFKAPSFPSVASTFTIQSPKKSELALTCEAQSYPVPIFKWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWTTAPDPTTGVGRLMSNDGILITKTTQRISMLSIESVHARHRANYTCVARNAAGVIYHTAELRVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELSAEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV |
Keywords
- PTM
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 39-134 | Ig-like | ||||
Sequence: PVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVR | ||||||
Domain | 138-230 | Ig-like | ||||
Sequence: AQYYDTDVNKAYVIRGNAAVLKCEIPSFVADFVSVVSWHTDQNEDFLPGSEYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLS | ||||||
Domain | 250-339 | Ig-like | ||||
Sequence: PSVASTFTIQSPKKSELALTCEAQSYPVPIFKWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLT | ||||||
Domain | 343-422 | Ig-like | ||||
Sequence: PLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELK | ||||||
Domain | 429-523 | Ig-like | ||||
Sequence: PPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLN | ||||||
Domain | 528-614 | Ig-like | ||||
Sequence: PYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQ | ||||||
Domain | 619-716 | Ig-like | ||||
Sequence: PQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWTTAPDPTTGVGRLMSNDGILITKTTQRISMLSIESVHARHRANYTCVARNAAGVIYHTAELR | ||||||
Domain | 721-813 | Ig-like | ||||
Sequence: PRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMIS | ||||||
Domain | 818-910 | Ig-like | ||||
Sequence: PEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASIN | ||||||
Domain | 919-1013 | Fibronectin type-III | ||||
Sequence: MPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEE | ||||||
Domain | 1018-1122 | Fibronectin type-III | ||||
Sequence: KPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQ | ||||||
Domain | 1123-1219 | Fibronectin type-III | ||||
Sequence: PPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPD | ||||||
Domain | 1223-1316 | Fibronectin type-III | ||||
Sequence: APTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQ | ||||||
Domain | 1318-1400 | Ig-like | ||||
Sequence: PAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSIT | ||||||
Domain | 1408-1501 | Fibronectin type-III | ||||
Sequence: PPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQ | ||||||
Domain | 1505-1600 | Fibronectin type-III | ||||
Sequence: LPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGT | ||||||
Region | 1694-1725 | Disordered | ||||
Sequence: PGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPN | ||||||
Region | 1793-1852 | Disordered | ||||
Sequence: GHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPA | ||||||
Compositional bias | 1815-1842 | Polar residues | ||||
Sequence: HSRSGSQSMPRANRYQRKNSQGGQSSIY | ||||||
Region | 1868-2022 | Disordered | ||||
Sequence: SQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV | ||||||
Compositional bias | 1954-1971 | Basic and acidic residues | ||||
Sequence: SNEISEAECDRDHGPRGN | ||||||
Compositional bias | 1981-1998 | Basic and acidic residues | ||||
Sequence: PKDQRTTEEMRKLIERNE | ||||||
Compositional bias | 2000-2014 | Polar residues | ||||
Sequence: GPKQLQLQQANGAGF |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,022
- Mass (Da)223,013
- Last updated2007-02-06 v1
- Checksum7CD01B2EB6B62A31
Computationally mapped potential isoform sequences
There are 61 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q0E9H9 | DSCA1_DROME | Dscam1 | 2016 | ||
A0A0B4K6Y9 | A0A0B4K6Y9_DROME | Dscam1 | 2020 | ||
A0A0B4K6Z3 | A0A0B4K6Z3_DROME | Dscam1 | 2019 | ||
A0A0B4K6Z8 | A0A0B4K6Z8_DROME | Dscam1 | 2016 | ||
A0A0B4K6Q9 | A0A0B4K6Q9_DROME | Dscam1 | 2035 | ||
A0A0B4K6R4 | A0A0B4K6R4_DROME | Dscam1 | 2035 | ||
A0A0B4K6R8 | A0A0B4K6R8_DROME | Dscam1 | 2019 | ||
A0A0B4K6S2 | A0A0B4K6S2_DROME | Dscam1 | 2036 | ||
A0A0B4K7H7 | A0A0B4K7H7_DROME | Dscam1 | 2020 | ||
A0A0B4K7H9 | A0A0B4K7H9_DROME | Dscam1 | 2030 | ||
A0A0B4K7I3 | A0A0B4K7I3_DROME | Dscam1 | 2036 | ||
A0A0B4K7I5 | A0A0B4K7I5_DROME | Dscam1 | 2016 | ||
A0A0B4K823 | A0A0B4K823_DROME | Dscam1 | 2038 | ||
A0A0B4K824 | A0A0B4K824_DROME | Dscam1 | 2035 | ||
A0A0B4K827 | A0A0B4K827_DROME | Dscam1 | 2028 | ||
A0A0B4K828 | A0A0B4K828_DROME | Dscam1 | 2032 | ||
A0A0B4K7T4 | A0A0B4K7T4_DROME | Dscam1 | 2035 | ||
A0A0B4K7T5 | A0A0B4K7T5_DROME | Dscam1 | 2033 | ||
A0A0B4K7T6 | A0A0B4K7T6_DROME | Dscam1 | 2019 | ||
A0A0B4K7T8 | A0A0B4K7T8_DROME | Dscam1 | 2034 | ||
A1Z6X1 | A1Z6X1_DROME | Dscam1 | 2019 | ||
A1Z6X3 | A1Z6X3_DROME | Dscam1 | 2016 | ||
A0A0C4DHD8 | A0A0C4DHD8_DROME | Dscam1 | 2016 | ||
A0A0B4KEF4 | A0A0B4KEF4_DROME | Dscam1 | 1947 | ||
Q0E9K1 | Q0E9K1_DROME | Dscam1 | 2030 | ||
Q0E9K5 | Q0E9K5_DROME | Dscam1 | 2032 | ||
Q0E9K6 | Q0E9K6_DROME | Dscam1 | 2016 | ||
Q0E9K8 | Q0E9K8_DROME | Dscam1 | 2037 | ||
Q0E9L1 | Q0E9L1_DROME | Dscam1 | 2020 | ||
Q0E9L2 | Q0E9L2_DROME | Dscam1 | 2034 | ||
Q0E9L3 | Q0E9L3_DROME | Dscam1 | 2034 | ||
Q0E9L4 | Q0E9L4_DROME | Dscam1 | 2018 | ||
Q0E9L6 | Q0E9L6_DROME | Dscam1 | 2034 | ||
Q0E9L7 | Q0E9L7_DROME | Dscam1 | 2034 | ||
Q0E9L8 | Q0E9L8_DROME | Dscam1 | 2019 | ||
Q0E9L9 | Q0E9L9_DROME | Dscam1 | 2018 | ||
Q0E9M0 | Q0E9M0_DROME | Dscam1 | 2030 | ||
Q0E9M1 | Q0E9M1_DROME | Dscam1 | 2035 | ||
Q0E9M2 | Q0E9M2_DROME | Dscam1 | 2035 | ||
Q0E9M3 | Q0E9M3_DROME | Dscam1 | 2020 | ||
Q0E9M4 | Q0E9M4_DROME | Dscam1 | 2035 | ||
Q0E9I0 | Q0E9I0_DROME | Dscam1 | 2017 | ||
Q0E9I1 | Q0E9I1_DROME | Dscam1 | 2016 | ||
Q0E9I2 | Q0E9I2_DROME | Dscam1 | 2031 | ||
Q0E9I3 | Q0E9I3_DROME | Dscam1 | 2017 | ||
Q0E9I5 | Q0E9I5_DROME | Dscam1 | 2013 | ||
Q0E9I6 | Q0E9I6_DROME | Dscam1 | 2032 | ||
Q0E9I7 | Q0E9I7_DROME | Dscam1 | 2016 | ||
Q0E9I8 | Q0E9I8_DROME | Dscam1 | 2019 | ||
Q0E9I9 | Q0E9I9_DROME | Dscam1 | 2031 | ||
Q0E9J1 | Q0E9J1_DROME | Dscam1 | 2017 | ||
Q0E9J2 | Q0E9J2_DROME | Dscam1 | 2031 | ||
Q0E9J3 | Q0E9J3_DROME | Dscam1 | 2016 | ||
Q0E9J4 | Q0E9J4_DROME | Dscam1 | 2031 | ||
Q0E9J5 | Q0E9J5_DROME | Dscam1 | 2031 | ||
Q0E9J6 | Q0E9J6_DROME | Dscam1 | 2017 | ||
Q0E9K0 | Q0E9K0_DROME | Dscam1 | 2016 | ||
Q0E9K2 | Q0E9K2_DROME | Dscam1 | 2017 | ||
Q0E9K3 | Q0E9K3_DROME | Dscam1 | 2030 | ||
Q0E9H5 | Q0E9H5_DROME | Dscam1 | 2031 | ||
Q0E9H7 | Q0E9H7_DROME | Dscam1 | 2017 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1815-1842 | Polar residues | ||||
Sequence: HSRSGSQSMPRANRYQRKNSQGGQSSIY | ||||||
Compositional bias | 1954-1971 | Basic and acidic residues | ||||
Sequence: SNEISEAECDRDHGPRGN | ||||||
Compositional bias | 1981-1998 | Basic and acidic residues | ||||
Sequence: PKDQRTTEEMRKLIERNE | ||||||
Compositional bias | 2000-2014 | Polar residues | ||||
Sequence: GPKQLQLQQANGAGF |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE013599 EMBL· GenBank· DDBJ | AAS64901.1 EMBL· GenBank· DDBJ | Genomic DNA |