A1U560 · TPMT_MARN8
- ProteinThiopurine S-methyltransferase
- Genetpm
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids219 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 10 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: W | ||||||
Binding site | 45 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 66 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 123 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | thiopurine S-methyltransferase activity | |
Biological Process | methylation | |
Biological Process | response to metal ion |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThiopurine S-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Marinobacteraceae > Marinobacter
Accessions
- Primary accessionA1U560
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000047206 | 1-219 | Thiopurine S-methyltransferase | |||
Sequence: MEHEFWHERWAKDQIGFHEGTVNQYLHDHWPELAGNGTDAVFVPLCGKAHDMWWLHDRGHPIIGVELSEVACKDFFEEAQEKASVHPGEPFTTFRHDDLQIWCGDYFQLVPDDLKHIRLVYDRAALIALPPEMRKSYVNHLTAIIPDDTRILLITLDYDSSEMQGPPFNVTDDEVFRLYGEDYEINQVLKRDMARDNPFAKRRGLRNGATESVFTLVKK |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length219
- Mass (Da)25,493
- Last updated2007-02-06 v1
- Checksum370A45E003976AF0
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000514 EMBL· GenBank· DDBJ | ABM20129.1 EMBL· GenBank· DDBJ | Genomic DNA |