A1TY30 · RNPH_MARN8

Function

function

Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

Catalytic activity

Features

Showing features for binding site.

123820406080100120140160180200220
TypeIDPosition(s)Description
Binding site86phosphate (UniProtKB | ChEBI); substrate
Binding site124-126phosphate (UniProtKB | ChEBI); substrate

GO annotations

AspectTerm
Molecular Function3'-5'-RNA exonuclease activity
Molecular FunctiontRNA binding
Molecular FunctiontRNA nucleotidyltransferase activity
Biological ProcessrRNA catabolic process
Biological ProcessrRNA processing
Biological ProcesstRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease PH
  • EC number
  • Short names
    RNase PH
  • Alternative names
    • tRNA nucleotidyltransferase

Gene names

    • Name
      rph
    • Ordered locus names
      Maqu_0548

Organism names

Accessions

  • Primary accession
    A1TY30

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000248231-238Ribonuclease PH

Interaction

Subunit

Homohexameric ring arranged as a trimer of dimers.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the RNase PH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    238
  • Mass (Da)
    25,724
  • Last updated
    2007-02-06 v1
  • Checksum
    FFF0AB396C62E1E2
MRPSGRTPEQPRDVRITRNYTRHAEGSVLVEFGDTKVICTASVENKVPPFLRGEGKGWITAEYGMLPRSTGSRMGREAARGKQGGRTVEIQRLIGRSLRAAVDLEALGEHTITIDCDVIQADGGTRTAAITGGCVALVDALNHLVKEKRLKKSPLKQMVAAVSVGVYRGTPVADLDYPEDSEAETDMNVIMTDQGGFIEIQGTAEGAPFEQAELDAMLALARKAIDQLFELQKEALSA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000514
EMBL· GenBank· DDBJ
ABM17649.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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