A1ST34 · RF3_PSYIN
- ProteinPeptide chain release factor 3
- GeneprfC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids528 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 20-27 | GTP (UniProtKB | ChEBI) | |||
Binding site | 88-92 | GTP (UniProtKB | ChEBI) | |||
Binding site | 142-145 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | guanosine tetraphosphate binding | |
Molecular Function | translation release factor activity, codon nonspecific | |
Molecular Function | translation release factor activity, codon specific | |
Biological Process | regulation of translational termination |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended namePeptide chain release factor 3
- Short namesRF-3
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Psychromonadaceae > Psychromonas
Accessions
- Primary accessionA1ST34
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000023672 | 1-528 | Peptide chain release factor 3 | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 11-279 | tr-type G | |||
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length528
- Mass (Da)59,481
- Last updated2007-02-06 v1
- MD5 Checksum9A8D3B8E1BCFB48632C7894D7AC52809
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000510 EMBL· GenBank· DDBJ | ABM02649.1 EMBL· GenBank· DDBJ | Genomic DNA |