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A1RQJ4 · A1RQJ4_PYRIL

Function

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.

Features

Showing features for binding site, active site.

133650100150200250300
Type
IDPosition(s)Description
Binding site123Zn2+ (UniProtKB | ChEBI); catalytic
Binding site125Zn2+ (UniProtKB | ChEBI); catalytic
Binding site133Zn2+ (UniProtKB | ChEBI); catalytic
Active site202Schiff-base intermediate with substrate
Binding site2125-aminolevulinate 1 (UniProtKB | ChEBI)
Binding site2245-aminolevulinate 1 (UniProtKB | ChEBI)
Binding site240Mg2+ (UniProtKB | ChEBI)
Active site255Schiff-base intermediate with substrate
Binding site2825-aminolevulinate 2 (UniProtKB | ChEBI)
Binding site3215-aminolevulinate 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionporphobilinogen synthase activity
Molecular Functionzinc ion binding
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Delta-aminolevulinic acid dehydratase
  • EC number

Gene names

    • Ordered locus names
      Pisl_0042

Organism names

Accessions

  • Primary accession
    A1RQJ4

Proteomes

Subcellular Location

Interaction

Subunit

Homooctamer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the ALAD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    336
  • Mass (Da)
    37,077
  • Last updated
    2007-02-06 v1
  • MD5 Checksum
    BA0A26E6A9422686CA360AFA50A5DF8B
MKFPTVRPRRLRTNKIIRDAVAETALDPSDFIYPIFVKEGPGREAIPTMPGQHRWPVGEELIKHVEEALALGVNKFILFGVVPEEQKDPHGSRGYDPEGPVPKALRLLKETFGDKILLFADVCLCEYTDHGHCGVVKTTGGRWHIDNDETIKLYAKEALVYADAGADFVAPSGMMDGQVAEIRKALDAHGFHHVGIMAYSAKYASAFYGPFRTAAASAPKFGDRRTYQMDPRNAHEALKEVAMDLEEGADIVMVKPALAYLDVIRLVKQHYPWAPLAAYNVSGEYAMVKAAAAAGYIDERVVTLEILTAIKRAGADLILTYHAPEAAKWLKDGTPF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000504
EMBL· GenBank· DDBJ
ABL87226.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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