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A1RA24 · A1RA24_PAEAT

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site246Mg2+ (UniProtKB | ChEBI)
Binding site276Mg2+ (UniProtKB | ChEBI)
Binding site278Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmagnesium ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • Ordered locus names
      AAur_3391

Organism names

Accessions

  • Primary accession
    A1RA24

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-25Disordered
Domain150-320Transketolase N-terminal
Domain498-724Pyruvate dehydrogenase E1 component middle
Domain740-876Transketolase-like C-terminal

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    925
  • Mass (Da)
    102,460
  • Last updated
    2007-02-06 v1
  • MD5 Checksum
    3569C4E28F3A5ED95BDB63C09D5F8384
MDVAAGEETSHILSGLTAQLPDRDPEETAEWIESLDALIAEQGTERAQYIMRSLLQRAGARSVGVPMVTTTDYVNTIPVDQEAQFPGNEEFERRYRAYMRWNAAVMVHRAQRSDIGVGGHISTYAGAATLYEVGFNHFFRGKDHPSGGDQVFFQGHASPGMYARAFMEGRLTEEDLDGFRQEKSKAGHALSSYPHPRLMPDFWEFPTVSMGIGPMNAIYQAQSNRYLQNRGIKDTSDQQVWAFLGDGEMDEPESRGLLQLAANENLDNLNFVINCNLQRLDGPVRGNGKIMQELEAFFRGAGWNVIKVVWGREWDSLLEADTDGALVKIMNETPDGDYQTYKAESGGFVREHFFGKSPQTKDMVADLDDEQIWGLKRGGHDYRKVYAAYKAATEFKGKPTVILAKTVKGYGLGPHFEGRNATHQMKKLTMEDLKAFRDHLRIPISDDQLDADLYRPPYYHPGMDAPEIKYLMERRAELGGFVPERRRKHTEVVLPEAKSYEVAKRGSGKQQAATTMAFVRLLKDLMRDKNFGARFVPVVPDESRTFGMDAFFPTAKIYNPKGQNYLSVDRDLVLAYKESPAGQLIHPGINEAGAVAAFTAAGTAYATHGEPLVPIYVFYSMFGFQRTGDSFWAAADQMTRGFIIGATAGRTTLTGEGLQHADGHSPILASTNPAVKTYDPAYGYEIGHIIRHGLEEMYGPDSTDGTGEDRNVMYYLTVYNEPITQPAEPDNLDINGLLKGIYKLADAPETTGNGNRPTATILASGVSVPWALEAQRILNEDWNVAAEVWSVTSWNELRRDGLAAEEHAFLNPGQPARTPFITEQLKDTNGPVIAVSDYMKAVPDQIRQFIPNDFASLGADGFGFSDTRQAARRYFKNDTHSIVAKTLQLLAARGEVEEGAPSYAIDRYKLLDVNAGTTGGAGGDA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000474
EMBL· GenBank· DDBJ
ABM06963.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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