A1R7J5 · DDL_PAEAT
- ProteinD-alanine--D-alanine ligase
- Geneddl
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids378 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation.
Catalytic activity
- 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + phosphate + H+
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Binds 2 magnesium or manganese ions per subunit.
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 189-244 | ATP (UniProtKB | ChEBI) | |||
Binding site | 322 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 335 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 335 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 337 | Mg2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | D-alanine-D-alanine ligase activity | |
Molecular Function | metal ion binding | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameD-alanine--D-alanine ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Micrococcaceae > Paenarthrobacter
Accessions
- Primary accessionA1R7J5
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000341053 | 1-378 | D-alanine--D-alanine ligase | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length378
- Mass (Da)39,981
- Last updated2007-02-06 v1
- Checksum912B80574B38828F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000474 EMBL· GenBank· DDBJ | ABM07506.1 EMBL· GenBank· DDBJ | Genomic DNA |