A1R0C7 · COAD_BORT9

Function

function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

Features

Showing features for binding site, site.

116520406080100120140160
TypeIDPosition(s)Description
Binding site9substrate
Binding site9-10ATP (UniProtKB | ChEBI)
Binding site17ATP (UniProtKB | ChEBI)
Site17Transition state stabilizer
Binding site41substrate
Binding site75substrate
Binding site89substrate
Binding site90-92ATP (UniProtKB | ChEBI)
Binding site100ATP (UniProtKB | ChEBI)
Binding site125-131ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantetheine-phosphate adenylyltransferase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphopantetheine adenylyltransferase
  • EC number
  • Alternative names
    • Dephospho-CoA pyrophosphorylase
    • Pantetheine-phosphate adenylyltransferase
      (PPAT
      )

Gene names

    • Name
      coaD
    • Ordered locus names
      BT0702

Organism names

Accessions

  • Primary accession
    A1R0C7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001232661-165Phosphopantetheine adenylyltransferase

Interaction

Subunit

Homohexamer.

Structure

Family & Domains

Sequence similarities

Belongs to the bacterial CoaD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    165
  • Mass (Da)
    19,107
  • Last updated
    2009-04-14 v1
  • Checksum
    3A4B1C27E120728E
MRVALFPGSFDPITWGHIDLVKRASLIFDKVIVLVANNSAKSYLLSDIERYELTFEVIASLGWSRIFVDRYDGIILDYALKNNIGFIVRGVRAFHDFEFEFERYVVNNKLSPSIDIVFLPSSDKYLFVRSDLVKELIKNKNFDLSSFIPDLVQKKLKSKFIDKLS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000049
EMBL· GenBank· DDBJ
AAX18019.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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