A1L244 · SAC1B_DANRE

Function

function

Phosphoinositide phosphatase which catalyzes the hydrolysis of phosphatidylinositol 4-phosphate (PtdIns4P), phosphatidylinositol 3-phosphate (PtdIns3P) and has low activity towards phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2).

Catalytic activity

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentendoplasmic reticulum membrane
Cellular Componentendoplasmic reticulum-plasma membrane contact site
Cellular ComponentGolgi membrane
Molecular Functionphosphatase activity
Molecular Functionphosphatidylinositol-3-phosphate phosphatase activity
Molecular Functionphosphatidylinositol-4-phosphate phosphatase activity
Biological Processphosphatidylinositol dephosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphatidylinositol-3-phosphatase SAC1-B
  • EC number
  • Alternative names
    • Phosphatidylinositol-4-phosphate phosphatase
    • Suppressor of actin mutations 1-like protein B

Gene names

    • Name
      sacm1lb
    • ORF names
      zgc:158642

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A1L244

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-519Cytoplasmic
Transmembrane520-540Helical
Topological domain541-547Lumenal
Transmembrane548-568Helical
Topological domain569-586Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003171751-586Phosphatidylinositol-3-phosphatase SAC1-B

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain121-450SAC
Region451-586Essential for phosphatidylinositol-4-phosphate phosphatase activity

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    586
  • Mass (Da)
    66,932
  • Last updated
    2007-02-06 v1
  • Checksum
    501148B8A763F25D
MASTYNSFNLHTTAEKFYIEACDDGVGDVLAIDRVSTEKTLTVRKDVPPSAVTRPICGIMGTIRLVAGVYLIVITKKKKVGDLLGHAVWKASDFDIISYKKTVLHLTDNQMQDNKVFLSMLNSVLNTDGFYFATDYDLTHTLQRLSNTSPEFQEMTLLERADQRFVWNGHLLREFMAQPELHRFVFPVIHGFIAMRSCCINGKIFDWNLISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIIQYNGAKASFIQTRGSIPFYWSQRPNLKYKPKPQISKSINHLDGFQRHFDSQIIIYGKQVILNLVNQKGSEKPLEQAFAKMVGSLGNGMIKYIAFDFHKECSRMRWHRLQILVDTVAELQDEFGYFLVDSDGSVQMQQDGTFRSNCMDCLDRTNVVQSLLARRSLQSQLERMAVLHVGQRIEEQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLLMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYAVEEADMNTPLHEPKDWKFLTLPIIMVVAFSMCIICLLMAGDTWTETLAYVLFWGSASVVTGGVILFNGRDFVDAPRLVQKEKMD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC129344
EMBL· GenBank· DDBJ
AAI29345.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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