A1HSU9 · A1HSU9_9FIRM
- ProteinChaperonin GroEL
- GenegroEL
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids541 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
Catalytic activity
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 29-32 | ATP (UniProtKB | ChEBI) | |||
Binding site | 86-90 | ATP (UniProtKB | ChEBI) | |||
Binding site | 413 | ATP (UniProtKB | ChEBI) | |||
Binding site | 476-478 | ATP (UniProtKB | ChEBI) | |||
Binding site | 492 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | GroEL-GroES complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent protein folding chaperone | |
Molecular Function | isomerase activity | |
Molecular Function | unfolded protein binding | |
Biological Process | chaperone cofactor-dependent protein refolding | |
Biological Process | protein refolding | |
Biological Process | response to heat |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameChaperonin GroEL
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Negativicutes > Selenomonadales > Sporomusaceae > Thermosinus
Accessions
- Primary accessionA1HSU9
Proteomes
Subcellular Location
Interaction
Subunit
Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
Structure
Sequence
- Sequence statusComplete
- Length541
- Mass (Da)57,541
- Last updated2007-02-06 v1
- ChecksumA7A3841161688376
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAWL01000019 EMBL· GenBank· DDBJ | EAX46893.1 EMBL· GenBank· DDBJ | Genomic DNA |