A1HSE3 · A1HSE3_9FIRM

Function

function

Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site11[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site47[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site81[4Fe-4S] cluster 1 (UniProtKB | ChEBI)
Binding site155[4Fe-4S] cluster 2 (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site159[4Fe-4S] cluster 2 (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet
Binding site162[4Fe-4S] cluster 2 (UniProtKB | ChEBI); 4Fe-4S-S-AdoMet

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionaspartic acid methylthiotransferase activity
Molecular Functionmetal ion binding
Molecular Functionprotein methylthiotransferase activity
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribosomal protein uS12 methylthiotransferase RimO
  • EC number
  • Short names
    uS12 MTTase
    ; uS12 methylthiotransferase
  • Alternative names
    • Ribosomal protein uS12 (aspartate-C(3))-methylthiotransferase
    • Ribosome maturation factor RimO

Gene names

    • Name
      rimO
    • ORF names
      TcarDRAFT_0611

Organism names

Accessions

  • Primary accession
    A1HSE3

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-118MTTase N-terminal
Domain141-371Radical SAM core
Domain374-441TRAM

Sequence similarities

Belongs to the methylthiotransferase family. RimO subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    441
  • Mass (Da)
    49,318
  • Last updated
    2007-02-06 v1
  • Checksum
    E74B991EDDB1139D
MLKAGFVSLGCAKNLVDTEVMLGILTNNNIAIVDDPGDADILIVNTCGFIDSAKEESITTILQMAEYKKESNCRALIVAGCLGQRYQQELLDELPEVDAIVGTGAWHRIMEAVQAALSGQRVLVIGPTETIYDETMPRIYTTPKYSAYVKVAEGCSNCCSYCVIPLVRGRFRSRPQESIVSEVKRLAANGIKEINLIAQDTTSYGRDLYGQLQLPQLLRALVQIEGIEWIRLLYCYPRYFTDELIEVIAKEPKICKYVDLPLQHIHDDILKAMHRRDSRFDIESLLAKIRKAIPDVAIRTSFIVGFPGETDDHFQVLQEFMQVQKFDHVGIFTYSQEEGTVAGAMADQVPEEVKQERYHALMALQCQISEEINRQLEGRVLKVLVEGKSDQPGVVFGRSYREAPDVDGRVYVEGAPGSRAGDLIVAKVVQGFTYDLLAEKI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AAWL01000015
EMBL· GenBank· DDBJ
EAX47103.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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