A1D9C9 · XYL2_NEOFI

Function

function

Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 4/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site47Zn2+ (UniProtKB | ChEBI); catalytic
Binding site72Zn2+ (UniProtKB | ChEBI); catalytic
Binding site73Zn2+ (UniProtKB | ChEBI); catalytic
Binding site182-187NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionD-xylulose reductase activity
Molecular FunctionL-iditol 2-dehydrogenase (NAD+) activity
Molecular Functionzinc ion binding
Biological ProcessD-xylose metabolic process
Biological ProcessL-arabinose catabolic process to xylulose 5-phosphate
Biological Processsorbitol catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable D-xylulose reductase A
  • EC number
  • Alternative names
    • Xylitol dehydrogenase A

Gene names

    • Name
      xdhA
    • ORF names
      NFIA_115270

Organism names

Accessions

  • Primary accession
    A1D9C9

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003935151-358Probable D-xylulose reductase A

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    358
  • Mass (Da)
    38,085
  • Last updated
    2007-01-23 v1
  • Checksum
    AA0A6C0EBE049730
MSTSTATAQNLSFVLEGIHQVKFEDRPIPELKDPHDVLVNVKFTGICGSDVHYWEHGSIGQFVVKDPMVLGHESSGVISKVGSAVTGLKVGDRVAMEPGIPCRRCEPCKAGKYNLCEKMAFAATPPYDGTLAKFYVLPEDFCYKLPDNISLQEGALMEPLGVAVHIVRQASVTPGQSVIVFGAGPVGLLCCAVAKAFGAAKIIAVDIQKPRLDFAKRYAATSTFEPAKVSAVDNADRLRKENNLGVGADVVIDASGAEPSVHTGIHVLRPGGTYVQGGMGRSEIMFPIMAACTKELTFKGSFRYGSGDYKLAVGLVASGRVNVKDLITGVVEFHDAEQAFKEVKAGKGIKTLIAGIQD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DS027692
EMBL· GenBank· DDBJ
EAW20990.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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