A1CGN9 · MTNA_ASPCL
- ProteinMethylthioribose-1-phosphate isomerase
- Genemri1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids385 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
Catalytic activity
- S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.
Features
Showing features for site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 173 | Transition state stabilizer | ||||
Sequence: C | ||||||
Active site | 255 | Proton donor | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | S-methyl-5-thioribose-1-phosphate isomerase activity | |
Biological Process | L-methionine salvage from methylthioadenosine | |
Biological Process | L-methionine salvage from S-adenosylmethionine |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethylthioribose-1-phosphate isomerase
- EC number
- Short namesM1Pi ; MTR-1-P isomerase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Fumigati
Accessions
- Primary accessionA1CGN9
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000402012 | 1-385 | Methylthioribose-1-phosphate isomerase | |||
Sequence: MTLEAIRYSTGKLVIIDQLQLPYVEKYIEVPTSKDAWHAIKKMRVRGAPAIAIVAALALASELHTLMAHDKLSNRAEEVRLFIQEKLDYLVSSRPTAVNLSDAARKLAAHVSDHAEMPNSTGRAVAEAFIQAAEEMLAKDLKDNTNIGKYGAEWIIRNALAGGRSKATILTHCNTGSLATSGYGTALGVIRALASKNALAYAYCTETRPYNQGSRLTAYELVHENLPATLVTDSMVAALLAKAEAAVDAIVVGADRVAANGDTANKIGTYALAVLAKFHGVKFLVAAPLTTIDRSTKSGADIVIEERPASEVTTIKGAVETESSCDRIKLETVRIAAEGIHVWNPAFDVTPSALIDAIITERGVVERGTDGRYNFDGIFEDHSAF |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length385
- Mass (Da)41,333
- Last updated2007-01-23 v1
- ChecksumA50076C7E72C658E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DS027054 EMBL· GenBank· DDBJ | EAW10044.1 EMBL· GenBank· DDBJ | Genomic DNA |