A1CGD1 · ABFB_ASPCL
- ProteinProbable alpha-L-arabinofuranosidase B
- GeneabfB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids506 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose. Able to hydrolyze 1,5-, 1,3- and 1,2-alpha-linkages not only in L-arabinofuranosyl oligosaccharides, but also in polysaccharides containing terminal non-reducing L-arabinofuranoses in side chains, like L-arabinan, arabinogalactan and arabinoxylan (By similarity).
Catalytic activity
Pathway
Glycan metabolism; L-arabinan degradation.
Features
Showing features for site, binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 184-185 | Cis-peptide bond | ||||
Sequence: CC | ||||||
Binding site | 227 | substrate | ||||
Sequence: D | ||||||
Active site | 229 | Nucleophile | ||||
Sequence: E | ||||||
Binding site | 230 | substrate | ||||
Sequence: N | ||||||
Binding site | 304 | substrate | ||||
Sequence: G | ||||||
Active site | 305 | Proton donor | ||||
Sequence: D | ||||||
Binding site | 424 | substrate | ||||
Sequence: H | ||||||
Binding site | 426 | substrate | ||||
Sequence: N | ||||||
Binding site | 427 | substrate | ||||
Sequence: F | ||||||
Binding site | 443 | substrate | ||||
Sequence: D | ||||||
Binding site | 471 | substrate | ||||
Sequence: H | ||||||
Binding site | 476 | substrate | ||||
Sequence: L | ||||||
Binding site | 496 | substrate | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | alpha-L-arabinofuranosidase activity | |
Biological Process | arabinan catabolic process | |
Biological Process | arabinose metabolic process | |
Biological Process | L-arabinose metabolic process | |
Biological Process | pectin catabolic process | |
Biological Process | xylan catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable alpha-L-arabinofuranosidase B
- EC number
- Short namesABF B; Arabinosidase B
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Fumigati
Accessions
- Primary accessionA1CGD1
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-26 | |||||
Sequence: MLSQPSRERAFVLALGLVVSSSLAAA | ||||||
Chain | PRO_0000394603 | 27-506 | Probable alpha-L-arabinofuranosidase B | |||
Sequence: APCDIYSSGGTPCVAAHSTTRALYSAYSGPLYQVKRGSDGATTNIAPRSAGGVANAAAQDTFCASMTCLITVIYDQSGRGNHLTQAPPGGFKGPEANGYDNLASAIGAPVTLNGQKAYGVFISPGTGYRNNAASGTAIGDAAEGMYAVLDGTHYNGGCCFDYGNAETSSLDTGNGHMEAIYFGTNTVWGSGSGSGPWIMADLENGLFSGSSPANNAGDPSVSYRFLTAAIKGGPNRWAIRGANAASGSLATYYSGARPNASGYNPMSKEGAIILGIGGDNSNGAQGTFYEGVMTSGYPSDATENAVQADIVAANYAVTSLTSGPALTVGSAISLRATTSCCTTRYLAHTGSTINTQVVSSASATTLKQQATWTVRTGLANSGCFSFESKDTPGSFIRHSNFALVLNGNDGTKQFKEDATFCPQAGLNGQGSSIRSWSFPTRYFRHYSNVLYAASNGGVHTFDAAGSFNDDVSWVISSGFA | ||||||
Disulfide bond | 29↔39 | |||||
Sequence: CDIYSSGGTPC | ||||||
Disulfide bond | 89↔94 | |||||
Sequence: CASMTC | ||||||
Disulfide bond | 184↔185 | |||||
Sequence: CC | ||||||
Glycosylation | 285 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 409↔447 | |||||
Sequence: CFSFESKDTPGSFIRHSNFALVLNGNDGTKQFKEDATFC |
Keywords
- PTM
PTM databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 27-343 | Catalytic | ||||
Sequence: APCDIYSSGGTPCVAAHSTTRALYSAYSGPLYQVKRGSDGATTNIAPRSAGGVANAAAQDTFCASMTCLITVIYDQSGRGNHLTQAPPGGFKGPEANGYDNLASAIGAPVTLNGQKAYGVFISPGTGYRNNAASGTAIGDAAEGMYAVLDGTHYNGGCCFDYGNAETSSLDTGNGHMEAIYFGTNTVWGSGSGSGPWIMADLENGLFSGSSPANNAGDPSVSYRFLTAAIKGGPNRWAIRGANAASGSLATYYSGARPNASGYNPMSKEGAIILGIGGDNSNGAQGTFYEGVMTSGYPSDATENAVQADIVAANYAV | ||||||
Region | 344-506 | ABD | ||||
Sequence: TSLTSGPALTVGSAISLRATTSCCTTRYLAHTGSTINTQVVSSASATTLKQQATWTVRTGLANSGCFSFESKDTPGSFIRHSNFALVLNGNDGTKQFKEDATFCPQAGLNGQGSSIRSWSFPTRYFRHYSNVLYAASNGGVHTFDAAGSFNDDVSWVISSGFA |
Domain
Organized into two domains: an N-terminal catalytic domain and a C-terminal arabinose-binding domain (ABD).
Sequence similarities
Belongs to the glycosyl hydrolase 54 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length506
- Mass (Da)51,886
- Last updated2007-01-23 v1
- ChecksumCDEB3D1906F35DD2
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DS027053 EMBL· GenBank· DDBJ | EAW11011.1 EMBL· GenBank· DDBJ | Genomic DNA |